ArticleNeurotoxicology2017
Association of neurobehavioral performance with R2* in the caudate nucleus of asymptomatic welders.
Article in Neurotoxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Effects of Subchronic Manganese and Iron Exposure, Alone or in Combination, on Elemental Distribution in Rats.Biological trace element research · 2025Article
- Higher hippocampal diffusivity values in welders are associated with greater R2* in the red nucleus and lower psychomotor performance.Neurotoxicology · 2023Article
- Synergic control in asymptomatic welders during multi-finger force exertion and load releasing while standing.Neurotoxicology · 2022Article
- Higher R2* in the Red Nucleus Is Associated With Lead Exposure in an Asymptomatic Welder Cohort.Toxicological sciences : an official journal of the Society of Toxicology · 2022Article
- PI3K/Akt Signaling Pathway Ameliorates Oxidative Stress-Induced Apoptosis upon Manganese Exposure in PC12 Cells.Biological trace element research · 2022Article
- The effects of occupational exposure to manganese fume on neurobehavioral and neurocognitive functions: An analytical cross-sectional study among welders.EXCLI journal · 2020Article
- Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein.Science signaling · 2019Article
- Article
- Welding-related brain and functional changes in welders with chronic and low-level exposure.Neurotoxicology · 2018Article
- Distinct neuroimaging features define Parkinson's disease and welding-related neurotoxicity.The neurologist (Hyderabad, India) · 2017Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesWelding fumes contain several metals including manganese (Mn) and iron (Fe) that may affect the nervous system. Previous studies of potential welding-related neurotoxicity have focused primarily on Mn exposure. The current study examined neurobehavioral and brain imaging changes in asymptomatic welders and their associations with both Mn and Fe exposure measurements.
methodsData were obtained from subjects with (n=46) and without (controls; n=31) a history of welding exposure. Occupational questionnaires estimated recent (HrsW; welding hours and E
resultsCompared to controls, welders had significantly higher R2* in the CN and lower performance on the Phonemic Fluency test. Correlation analyses revealed that welders' Phonemic Fluency scores were inversely associated with R2* in the CN, but not with the PI or R1 in any brain region of interest studied. DISCUSSION: The results showed that neurobehavioral performance for the asymptomatic welders in our study was worse than individuals who had not welded, and suggest the differences may be associated with higher Fe accumulation in the CN.
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