ArticleHormones and behavior2017
The effects of long-term estradiol treatment on social behavior and gene expression in adult female rats.
Article in Hormones and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Under or Absent Reporting of Light Stimuli in Testing of Anxiety-Like Behaviors in Rodents: The Need for Standardization.Frontiers in molecular neuroscience · 2022Pooled it
- Impact of Circulating Estrogen and Mild Systemic Dehydration on Ultrasonic Vocalizations in Female Rats.Journal of speech, language, and hearing research : JSLHR · 2026Article
- Chronic 17β-estradiol treatment improves negative valence, anhedonic profile, and social interactions in ovariectomized, middle-aged female rats.Frontiers in behavioral neuroscience · 2025Article
- Altered vocal communication in adult vasopressin-deficient Brattleboro rats.Physiology & behavior · 2024Article
- Article
- NMDA receptor-mediated synaptic transmission in prefrontal neurons underlies social memory retrieval in female mice.Neuropharmacology · 2022Article
- Impact of pubertal onset on region-specific Esr2 expression.Journal of neuroendocrinology · 2021Article
- Epigenetic Modulation of Vasopressin Expression in Health and Disease.International journal of molecular sciences · 2021Review
- EDCs Reorganize Brain-Behavior Phenotypic Relationships in Rats.Journal of the Endocrine Society · 2021Article
- Biological and Acoustic Sex Differences in Rat Ultrasonic Vocalization.Brain sciences · 2021Review
- Estradiol treatment improves biological rhythms in a preclinical rat model of menopause.Neurobiology of aging · 2019Article
- Endocrine-disrupting chemicals: Effects on neuroendocrine systems and the neurobiology of social behavior.Hormones and behavior · 2019Review
- Impaired innate and conditioned social behavior in adult C57Bl6/J mice prenatally exposed to chlorpyrifos.Behavioral and brain functions : BBF · 2019Article
- Social and neuromolecular phenotypes are programmed by prenatal exposures to endocrine-disrupting chemicals.Molecular and cellular endocrinology · 2019Article
- Total Polysaccharides of Lily Bulb Ameliorate Menopause-Like Behavior in Ovariectomized Mice: Multiple Mechanisms Distinct from Estrogen Therapy.Oxidative medicine and cellular longevity · 2019Article
- Effects of the Endocrine-Disrupting Chemicals, Vinclozolin and Polychlorinated Biphenyls, on Physiological and Sociosexual Phenotypes in F2 Generation Sprague-Dawley Rats.Environmental health perspectives · 2018Article
- The timing and duration of estradiol treatment in a rat model of the perimenopause: Influences on social behavior and the neuromolecular phenotype.Hormones and behavior · 2018Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
This study tested the effects of long-term estradiol (E
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.