Evidence map›Paper›PMID 27871812›Full record

ArticleBone2017

Effects of Roux-en-Y gastric bypass and sleeve gastrectomy on bone mineral density and marrow adipose tissue.

Miriam A Bredella, Logan B Greenblatt, Alireza Eajazi, Martin Torriani, Elaine W Yu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bone, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 9 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 9 syntheses or guidelines pooled it, 169 citations in OpenAlex.

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  4. Changes in volumetric bone mineral density and bone quality after Roux-en-Y gastric bypass: A meta-analysis with meta-regression.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
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  8. The change of bone mineral density and bone metabolism after gastrectomy for gastric cancer: a meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Miriam A BredellaDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Logan B GreenblattEndocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Alireza EajaziDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Martin TorrianiDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Elaine W YuEndocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States. Electronic address: ewyu@partners.org.
Harvard University · USMassachusetts General Hospital · US

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTOPHER P DUGGAN · 1994 to 2026
$31.6M
Skeletal health in obesity and after bariatric surgeryK23DK093713 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI YU, ELAINE WEI-YIN · 2012 to 2016
$788k
Comparative and long-term effects of bariatric surgery on bone healthR03DK107869 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI YU, ELAINE WEI-YIN · 2016 to 2017
$157k
NCATS NIH HHS UL1 TR001102NIDDK NIH HHS K23 DK093713NIDDK NIH HHS L30 DK089544NIDDK NIH HHS P30 DK040561NIDDK NIH HHS R03 DK107869
6 · The paper itself

Abstract

Bariatric surgery is associated with bone loss but skeletal consequences may differ between Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), the two most commonly performed bariatric procedures. Furthermore, severe weight loss is associated with high marrow adipose tissue (MAT); however, MAT is also increased in visceral adiposity. The purpose of our study was to determine the effects of RYGB and SG on BMD and MAT. We hypothesized that both bariatric procedures would lead to a decrease in BMD and MAT. We studied 21 adults with morbid obesity (mean BMI 44.1±5.1kg/m

Indexed as

GastrectomyGastric BypassAdipose TissueBiomarkersBody CompositionBone DensityBone MarrowBone RemodelingDiabetes MellitusFemaleHormonesHumansMaleMiddle AgedBiomarkersHormonesBariatric surgeryBone mineral density (BMD)Dual-energy X-ray absorptiometryMarrow adipose tissue (MAT)Proton MR spectroscopyQuantitative computed tomography (QCT)

Identifiers

PMID27871812
PMCPMC5222731
OpenAlexW2552102528

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.