ReviewTrends in neurosciences2016
An Integrative Tinnitus Model Based on Sensory Precision.
Review in Trends in neurosciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
119 citing papers in PubMed, 3 syntheses or guidelines pooled it, 231 citations in OpenAlex.
- Psychosocial Variables That Predict Chronic and Disabling Tinnitus: A Systematic Review.Current topics in behavioral neurosciences · 2021Pooled it
- Auditory and visual hallucination prevalence in Parkinson's disease and dementia with Lewy bodies: a systematic review and meta-analysis.Psychological medicine · 2019Pooled it
- Associations Between Subjective Tinnitus and Cognitive Performance: Systematic Review and Meta-Analyses.Trends in hearingPooled it
- Altered parietal multisensory integration in chronic tinnitus during closed-loop real-time fMRI auditory downregulation.NeuroImage. Clinical · 2026Trial
- Tinnitus: A Dimensionally Segregated, yet Perceptually Integrated Heterogeneous Disorder.Journal of the Association for Research in Otolaryngology : JARO · 2024Trial
- Investigating the Efficacy of an Individualized Alpha/Delta Neurofeedback Protocol in the Treatment of Chronic Tinnitus.Neural plasticity · 2019Trial
- Review
- Stimulus statistical context sensitivity of deviant responses to auditory intensity changes.Scientific reports · 2026Article
- Auditory Network Discoherence in Chronic Tinnitus.medRxiv : the preprint server for health sciences · 2026Article
- Tinnitus severity and hearing loss: mechanistic insights and future directions.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Tinnitus.Nature reviews. Disease primers · 2026Review
- Article
- A Unified Theory for the Development of Tinnitus Perception and Hyperacusis Based on Associative Plasticity in the Dorsal Cochlear Nucleus.Brain sciences · 2026Article
- Integrating the Sensation-Emotion-Cognition (SEC) Model into Tinnitus Care: A Preliminary Exploratory Study of a Comprehensive Tinnitus Management Protocol.Audiology research · 2026Article
- Tinnitus perception is linked to arousal dysfunction.iScience · 2026Article
- Everolimus Attenuates Salicylate-Induced Tinnitus-Like Behavior and Auditory Cortical Hyperexcitability.Drug design, development and therapy · 2026Article
- Article
- Avatar therapy for bothersome tinnitus using an augmented reality mobile application: a pilot feasibility study.Frontiers in digital health · 2026Article
- Abnormally enhanced temporal correlations of alpha oscillations across multiple timescales in tinnitus patients.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Modulation of Auditory Cortex Activity in Salicylate-Induced Tinnitus Rats via Deep Brain Stimulation of the Inferior Colliculus.Brain and behavior · 2025Article
59 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
Tinnitus is a common disorder that often complicates hearing loss. Its mechanisms are incompletely understood. Current theories proposing pathophysiology from the ear to the cortex cannot individually - or collectively - explain the range of experimental evidence available. We propose a new framework, based on predictive coding, in which spontaneous activity in the subcortical auditory pathway constitutes a 'tinnitus precursor' which is normally ignored as imprecise evidence against the prevailing percept of 'silence'. Extant models feature as contributory mechanisms acting to increase either the intensity of the precursor or its precision. If precision (i.e., postsynaptic gain) rises sufficiently then tinnitus is perceived. Perpetuation arises through focused attention, which further increases the precision of the precursor, and resetting of the default prediction to expect tinnitus.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.