Evidence map›Paper›PMID 27871316›Full record

ArticleVeterinary research2016

Heterogeneous antigenic properties of the porcine reproductive and respiratory syndrome virus nucleocapsid.

Julie C F Rappe, Obdulio García-Nicolás, Franziska Flückiger, Barbara Thür, Martin A Hofmann, Artur Summerfield, Nicolas Ruggli

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Julie C F RappeThe Institute of Virology and Immunology IVI, Mittelhäusern, Switzerland.
Obdulio García-NicolásThe Institute of Virology and Immunology IVI, Mittelhäusern, Switzerland.
Franziska FlückigerThe Institute of Virology and Immunology IVI, Mittelhäusern, Switzerland.
Barbara ThürThe Institute of Virology and Immunology IVI, Mittelhäusern, Switzerland.
Martin A HofmannThe Institute of Virology and Immunology IVI, Mittelhäusern, Switzerland.
Artur SummerfieldThe Institute of Virology and Immunology IVI, Mittelhäusern, Switzerland.
Nicolas RuggliThe Institute of Virology and Immunology IVI, Mittelhäusern, Switzerland. nicolas.ruggli@ivi.admin.ch.ORCID 0000-0002-7679-6290
University of Bern · CHInstitute of Virology of the Slovak Academy of Sciences · SKNeue Kantonsschule Aarau · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) is an arterivirus responsible for a widespread contagious disease of domestic pigs with high economic impact. Switzerland is one of the rare PRRSV-free countries in Europe, although sporadic outbreaks have occurred in the past. The PRRSV isolate IVI-1173 from the short outbreak in Switzerland in 2012 was entirely sequenced, and a functional full-length cDNA clone was constructed. Genetic and antigenic characterization of IVI-1173 revealed the importance of amino acid 90 of the nucleocapsid protein N as part of a conformational epitope. IVI-1173 was not detected by SDOW17, a monoclonal antibody against N widely used to detect PRRSV-infected cells. Substitution of alanine at position 90 of N [N(A

Indexed as

AnimalsAntibodies, ViralAntigens, ViralDisease OutbreaksEpitopesFemaleFlow CytometryFluorescent Antibody TechniqueMaleNucleocapsidPhylogenyPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusSequence AlignmentSequence Analysis, DNASwineAntibodies, ViralAntigens, ViralEpitopes

Identifiers

PMID27871316
PMCPMC5118883
OpenAlexW2557180350

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.