ArticleParasites & vectors2016
Anaplasma phagocytophilum in sheep and goats in central and southeastern China.
Article in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Molecular Characterization and Prevalence of Anaplasma ovis and Anaplasma phagocytophilum in Goat Population in Siirt Province From Türkiye.Veterinary medicine and science · 2026Article
- Nationwide Survey of Vector-Borne Diseases in Rodents and Mites in Korea:Animals : an open access journal from MDPI · 2024Article
- Presence ofPathogens (Basel, Switzerland) · 2023Article
- Molecular Characterization ofAnimals : an open access journal from MDPI · 2022Article
- First Molecular Evidence for the Presence ofPathogens (Basel, Switzerland) · 2022Article
- Molecular Survey of Tick-Borne Pathogens Reveals Diversity and Novel Organisms With Veterinary and Public Health Significance in Wildlife From a National Nature Reserve of China.Frontiers in veterinary science · 2021Article
- First Molecular Detection ofPathogens (Basel, Switzerland) · 2020Article
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10 authors.
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Abstract
backgroundAnaplasma phagocytophilum is wide spread throughout the world and impacts both human and animal health. Several distinct ecological clusters and ecotypes of the agent have been established on the basis of various genetic loci. However, information on the genetic variability of A. phagocytophilum isolates in China represents a gap in knowledge. The objective of this study was to determine the prevalence and genetic characterization of A. phagocytophilum in small ruminants in central and southeastern China.
methodsThe presence of A. phagocytophilum was determined in 421 blood samples collected from small ruminants by PCR. Positive samples were genetically characterized based on 16S rRNA and groEL genes. Statistical analyses were conducted to identify ecotypes of A. phagocytophilum strains, to assess their host range and zoonotic potential.
resultsOut of 421 sampled small ruminants, 106 (25.2%) were positive for A. phagocytophilum. The positive rate was higher in sheep (35.1%, 40/114) than in goats (26.4%, 66/307) (P < 0.05). Sequence analyses revealed that the isolates identified in this study were placed on two separate clades, indicating that two 16S rRNA variants of A. phagocytophilum were circulating in small ruminants in China. However, analysis using obtained groEL sequences in this study formed one cluster, which was separate from other known ecotypes reported in Europe. In addition, a novel Anaplasma sp. was identified and closely related to an isolate previously reported in Hyalomma asiaticum, which clustered independently from all recognized Anaplasma species.
conclusionsA molecular survey of A. phagocytophilum was conducted in sheep and goats from ten provinces in central and southeastern China. Two 16S rRNA variants and a new ecotype of A. phagocytophilum were identified in small ruminants in China. Moreover, a potential novel Anaplasma species was reported in goats. Our findings provide additional information on the complexity of A. phagocytophilum in terms of genetic diversity in China.
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