Evidence map›Paper›PMID 27871266›Full record

ArticleBMC complementary and alternative medicine2016

Antioxidant, antidiarrheal, hypoglycemic and thrombolytic activities of organic and aqueous extracts of Hopea odorata leaves and in silico PASS prediction of its isolated compounds.

Mohammad Shah Hafez Kabir, Mohammed Munawar Hossain, Md Imtiazul Kabir, Shabbir Ahmad, Nishan Chakrabarty, Md Atiar Rahman, Md Mominur Rahman

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mohammad Shah Hafez KabirDepartment of Pharmacy, International Islamic University Chittagong, Chittagong, 4318, Bangladesh.
Mohammed Munawar HossainDepartment of Pharmacy, International Islamic University Chittagong, Chittagong, 4318, Bangladesh.
Md Imtiazul KabirDepartment of Pharmacy, International Islamic University Chittagong, Chittagong, 4318, Bangladesh.
Shabbir AhmadDepartment of Pharmacy, International Islamic University Chittagong, Chittagong, 4318, Bangladesh.
Nishan ChakrabartyDepartment of Pharmacy, International Islamic University Chittagong, Chittagong, 4318, Bangladesh.
Md Atiar RahmanDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, University of Chittagong, Chittagong, 4331, Bangladesh. atiar@cu.ac.bd.
Md Mominur RahmanDepartment of Pharmacy, International Islamic University Chittagong, Chittagong, 4318, Bangladesh.
International Islamic University Chittagong · BDUniversity of Chittagong · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHopea Odorata, locally known as Telsur (Bangladesh), has some traditional uses as folk medicine. This study aims to investigate the antioxidant, antidiarrheal, hypoglycemic and thrombolytic activities of H. odorata leaf extracts as new therapeutic prospects predicting the activity of some of the isolated compounds of this plant.

methodsLeaves of Hopea odorata was extracted with pure methanol (MEHO), ethanol (EEHO) and water (AEHO). The extract was tested for antioxidant activity by using reducing power and H

resultAmong the all extracts, MEHO exhibited strong antioxidant activity in both reducing power and H

conclusionThese findings suggest that the plant may be a potential source of new antidiarrheal, thrombolytic and antioxidative agents but it is found to have no antidiabetic capability. PASS prediction matched with present study for the extracts. Further study needs to identify the PASS predicted biological actions of the phytoconstituents.

Indexed as

AnimalsAntidiarrhealsAntioxidantsBlood CellsDiarrheaDipterocarpaceaeFemaleFibrinolytic AgentsHumansHypoglycemic AgentsMaleMiceMolecular StructurePlant ExtractsPlant LeavesAntidiarrhealsAntioxidantsFibrinolytic AgentsHypoglycemic AgentsPlant ExtractsAntidiarrhealAntioxidantH2O2 scavengingHopea odorataPASS predictionThrombolytic

Identifiers

PMID27871266
PMCPMC5117591
OpenAlexW2552412431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.