Evidence map›Paper›PMID 27870601›Full record

ArticleViral immunology

T Cell Immunity to Varicella-Zoster Virus in the Setting of Advanced HIV and Multiple Varicella-Zoster Virus Recurrences.

Rachel A Bender Ignacio, Meena S Ramchandani, Kerry J Laing, Christine M Johnston, David M Koelle

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Viral immunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Disseminated Herpes Zoster with Decreased CD4 Counts in a HIV-Infected Patient.Clinical, cosmetic and investigational dermatology · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachel A Bender Ignacio1 Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington , Seattle, Washington.
Meena S Ramchandani1 Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington , Seattle, Washington.
Kerry J Laing1 Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington , Seattle, Washington.
Christine M Johnston1 Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington , Seattle, Washington.
David M Koelle1 Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington , Seattle, Washington.

Funding

THE PERINATAL COMPLICATIONS OF ASYMPTOMATIC GENITAL HERPES SIMPLEX VIRUSP01AI030731 · NIAID · UNIVERSITY OF WASHINGTON · PI ZHU, JIA · 1991 to 2017
$34.3M
Interdisciplinary Tranining in Cancer ResearchT32CA080416 · NCI · UNIVERSITY OF WASHINGTON · PI STODDARD, BARRY L. · 1998 to 2023
$9.7M
Genomic systems approach to measure HSV-1-specific T-cell dominance in humansR01AI094019 · NIAID · UNIVERSITY OF WASHINGTON · PI KOELLE, DAVID M · 2012 to 2016
$1.9M
Determining the component causes of systemic immune activation that moderate HIV acquisition and establishment of the latent viral reservoirK23AI129659 · NIAID · UNIVERSITY OF WASHINGTON · PI BENDER IGNACIO, RACHEL ANN · 2017 to 2021
$868k
NCI NIH HHS T32 CA080416NIAID NIH HHS HHSN272201400049CNIAID NIH HHS K23 AI129659NIAID NIH HHS P01 AI030731NIAID NIH HHS R01 AI094019
6 · The paper itself

Abstract

A woman presented with at least four manifestations of varicella-zoster virus (VZV) infection, including central nervous system vasculitis, during her first 2 years of HIV infection. We evaluated her CD4 T cell responses to VZV given the infrequency with which multiple recurrences of VZV occurred, especially following immune reconstitution on antiretroviral therapy.

Indexed as

AdultCD4-Positive T-LymphocytesFemaleHerpesvirus 3, HumanHerpes ZosterHIV InfectionsHumansRecurrenceCD4 responsecellular immunologyherpes zosterHIVvaricella-zoster virusVZV vasculitis

Identifiers

PMID27870601
PMCPMC5220562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.