Evidence map›Paper›PMID 27870598›Full record

ReviewHuman vaccines & immunotherapeutics2017

Potential applications of nanoparticles in cancer immunotherapy.

Yimei Jia, Abdelwahab Omri, Lakshmi Krishnan, Michael J McCluskie

Open access · bronzeAbstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 45 citations in OpenAlex.

  1. Current Advances in Nanocarriers for Cancer Therapy.International journal of nanomedicine · 2025
    Review
  2. Nanoparticle-Mediated Immunotherapy in Triple-Negative Breast Cancer.ACS biomaterials science & engineering · 2024
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Foliate-Targeting Quantum Dots-International journal of molecular sciences · 2022
    Article
  8. Biomimetic nanoparticles for tumor immunotherapy.Frontiers in bioengineering and biotechnology · 2022
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Nanoparticle cancer vaccines: Design considerations and recent advances.Asian journal of pharmaceutical sciences · 2020
    Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Bioactive Nanoparticles for Cancer Immunotherapy.International journal of molecular sciences · 2018
    Review
  20. Nanoparticles as a promising method to enhance the abscopal effect in the era of new targeted therapies.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yimei Jiaa Human Health Therapeutics, National Research Council of Canada , Ottawa , Ontario , Canada.
Abdelwahab Omrib Biomolecular Sciences Program, Laurentian University , Sudbury , Ontario , Canada.
Lakshmi Krishnana Human Health Therapeutics, National Research Council of Canada , Ottawa , Ontario , Canada.
Michael J McCluskiea Human Health Therapeutics, National Research Council of Canada , Ottawa , Ontario , Canada.
National Research Council Canada · CALaurentian University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years considerable progress has been made in the field of cancer immunotherapy whereby treatments that modulate the body's own immune system are used to combat cancer. This has the potential to not only elicit strong anti-cancer immune responses which can break pre-existing tolerance and help promote tumor regression, but could also induce immunological memory which may help prevent tumor recurrence. In order to ensure effective delivery of immunotherapeutic agents, such as vaccines, checkpoint inhibitors, chemotherapeutic agents and nucleic acids, a safe and effective delivery system is often required. One such approach is the use of multifunctional nanoparticles (NPs), such as liposomes, polymers, micelles, dendrimers, inorganic NPs, and hybrid NPs, which have the potential to combine the delivery of a diverse range of therapeutic immunomodulators thereby increasing the efficacy of tumor cell killing. This review focuses on recent progress in NP-mediated immunotherapy for the treatment of cancer.

Indexed as

AnimalsDrug CarriersHumansImmunologic FactorsImmunotherapyNanoparticlesNeoplasmsDrug CarriersImmunologic Factorscancerdelivery systemimmunomodulationimmunotherapynanoparticles

Identifiers

PMID27870598
PMCPMC5287329
OpenAlexW2553273735

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.