ReviewThe Journal of physiology2016
Continuous attractor network models of grid cell firing based on excitatory-inhibitory interactions.
Review in The Journal of physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Distinct cell-type contributions and network topography of theta-nested gamma oscillations in the medial entorhinal cortex.bioRxiv : the preprint server for biology · 2026Article
- Article
- Fast spiking interneurons autonomously generate fast gamma oscillations in the medial entorhinal cortex with excitation strength tuning ING-PING transitions.bioRxiv : the preprint server for biology · 2025Article
- Spatial periodicity in grid cell firing is explained by a neural sequence code of 2-D trajectories.eLife · 2025Article
- Article
- A spatial transformation-based CAN model for information integration within grid cell modules.Cognitive neurodynamics · 2024Article
- Modeling the grid cell activity based on cognitive space transformation.Cognitive neurodynamics · 2024Article
- A Continuous Attractor Model with Realistic Neural and Synaptic Properties Quantitatively Reproduces Grid Cell Physiology.International journal of molecular sciences · 2024Article
- A Continuous Attractor Model with Realistic Neural and Synaptic Properties Quantitatively Reproduces Grid Cell Physiology.bioRxiv : the preprint server for biology · 2024Article
- Simulation of oscillatory dynamics induced by an approximation of grid cell output.Reviews in the neurosciences · 2023Review
- Empirically validated theoretical analysis of visual-spatial perception under change of nervous system arousal.Frontiers in computational neuroscience · 2023Article
- Article
- Microcircuits for spatial coding in the medial entorhinal cortex.Physiological reviews · 2022Review
- A Spiking Neural Network Model of Rodent Head Direction Calibrated With Landmark Free Learning.Frontiers in neurorobotics · 2022Article
- Spiking Neural Networks and Hippocampal Function: A Web-Accessible Survey of Simulations, Modeling Methods, and Underlying Theories.Cognitive systems research · 2021Article
- The grid code for ordered experience.Nature reviews. Neuroscience · 2021Review
- Spatially structured inhibition defined by polarized parvalbumin interneuron axons promotes head direction tuning.Science advances · 2021Article
- A Model of Spatial Cell Development in Rat Hippocampus Based on Artificial Neural Network.Journal of healthcare engineering · 2021Article
- Somatostatin expressing GABAergic interneurons in the medial entorhinal cortex preferentially inhibit layerCommunications biology · 2020Article
- Article
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Authors and funding
3 authors.
Funding
Abstract
Neurons in the medial entorhinal cortex encode location through spatial firing fields that have a grid-like organisation. The challenge of identifying mechanisms for grid firing has been addressed through experimental and theoretical investigations of medial entorhinal circuits. Here, we discuss evidence for continuous attractor network models that account for grid firing by synaptic interactions between excitatory and inhibitory cells. These models assume that grid-like firing patterns are the result of computation of location from velocity inputs, with additional spatial input required to oppose drift in the attractor state. We focus on properties of continuous attractor networks that are revealed by explicitly considering excitatory and inhibitory neurons, their connectivity and their membrane potential dynamics. Models at this level of detail can account for theta-nested gamma oscillations as well as grid firing, predict spatial firing of interneurons as well as excitatory cells, show how gamma oscillations can be modulated independently from spatial computations, reveal critical roles for neuronal noise, and demonstrate that only a subset of excitatory cells in a network need have grid-like firing fields. Evaluating experimental data against predictions from detailed network models will be important for establishing the mechanisms mediating grid firing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.