Evidence map›Paper›PMID 27870006›Full record

ArticleInternational journal of cancer2017

Prediagnostic circulating concentrations of plasma insulin-like growth factor-I and risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition.

Aurora Perez-Cornago, Paul N Appleby, Sarah Tipper, Timothy J Key, Naomi E Allen, Alexandra Nieters, Roel Vermeulen, Sandrine Roulland, Delphine Casabonne, Rudolf Kaaks and 30 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in International journal of cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors at 20 institutions in 13 countries.

Aurora Perez-CornagoNuffield Department of Population Health, Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom.
Paul N ApplebyNuffield Department of Population Health, Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom.
Sarah TipperNuffield Department of Population Health, Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom.
Timothy J KeyNuffield Department of Population Health, Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom.
Naomi E AllenClinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, United Kingdom.
Alexandra NietersCenter for Chronic Immunodeficiency, Molecular Epidemiology, University Medical Center Freiburg, Freiburg, Germany.
Roel VermeulenInstitute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands.
Sandrine RoullandCentre d'Immunologie de Marseille-Luminy, Université d'Aix-Marseille UM2, Inserm, U1104, CNRS, Marseille, France.
Delphine CasabonneUnit of Infections and Cancer (UNIC), IDIBELL, Institut Català d'Oncologia, 08907 L'Hospitalet de Llobregat, Barcelona, Spain.
Rudolf KaaksDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Renee T FortnerDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Heiner BoeingDepartment of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.
Antonia TrichopoulouHellenic Health Foundation, Athens, Greece.
Carlo La VecchiaHellenic Health Foundation, Athens, Greece.
Eleni KlinakiHellenic Health Foundation, Athens, Greece.
Louise HansenDanish Cancer Society Research Center, Copenhagen, Denmark.
Anne TjønnelandDanish Cancer Society Research Center, Copenhagen, Denmark.
Fabrice BonnetUniversité Paris-Saclay, Université Paris-Sud, UVSQ, CESP, INSERM, Villejuif, France.
Guy FagherazziUniversité Paris-Saclay, Université Paris-Sud, UVSQ, CESP, INSERM, Villejuif, France.
Marie-Christine Boutron-RuaultUniversité Paris-Saclay, Université Paris-Sud, UVSQ, CESP, INSERM, Villejuif, France.
Valeria PalaEpidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
Giovanna MasalaMolecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute-ISPO, Florence, Italy.
Carlotta SacerdoteUnit of Cancer Epidemiology, AO Citta' della Salute e della Scienza-University of Turin and Center for Cancer Prevention (CPO-Piemonte), Turin, Italy.
Petra H PeetersDepartment of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands.
H B As Bueno-de-MesquitaDepartment for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Elisabete WeiderpassDepartment of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.
Miren DorronsoroBasque Regional Health Department San Sebastian, Public Health Direction and Biodonostia- Ciberesp, Spain.
J Ramón QuirósPublic Health Directorate, Asturias, Spain.
Aurelio BarricarteCIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Diana GavrilaCIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Antonio AgudoUnit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.
Signe BorgquistDepartment of Clinical Sciences Lund, Division of Oncology and Pathology, Lund University, Faculty of Medicine, Lund, Sweden.
Ann H RosendahlDepartment of Clinical Sciences Lund, Division of Oncology and Pathology, Lund University, Faculty of Medicine, Lund, Sweden.
Beatrice MelinDepartment of Radiation Sciences, Oncology Umeå University, Umeå, Sweden.
Nick WarehamMRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.
Kay-Tee KhawUniversity of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Marc GunterDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Elio RiboliDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Paolo VineisDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Ruth C TravisNuffield Department of Population Health, Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom.
University of Oxford · GBImperial College London · GBDanish Cancer Society · DKHeidelberg University · DEHellenic Health Foundation · GRInstitut Català d'Oncologia · ESLund University · SEAthens State University · USBiogipuzkoa Health Research Institute · ESCentre d’Immunologie de Marseille-Luminy · FRFondazione IRCCS Istituto Nazionale dei Tumori · ITGerman Institute of Human Nutrition · DEGobierno del Principado de Asturias · ESInserm · FRInstituto de Salud Pública de Navarra · ESInstituto Murciano de Investigación Biosanitaria · ESKarolinska Institutet · SEMRC Epidemiology Unit · GBPiedmont Reference Center for Epidemiology and Cancer Prevention · ITUmeå University · SE

Funding

Cancer Research UK 14136Cancer Research UK 16491Medical Research Council G0401527Medical Research Council G1000143Medical Research Council MR/M012190/1Medical Research Council MR/N003284/1World Health Organization 001
6 · The paper itself

Abstract

Insulin-like growth factor (IGF)-I has cancer promoting activities. However, the hypothesis that circulating IGF-I concentration is related to risk of lymphoma overall or its subtypes has not been examined prospectively. IGF-I concentration was measured in pre-diagnostic plasma samples from a nested case-control study of 1,072 cases of lymphoid malignancies and 1,072 individually matched controls from the European Prospective Investigation into Cancer and Nutrition. Odds ratios (ORs) and confidence intervals (CIs) for lymphoma were calculated using conditional logistic regression. IGF-I concentration was not associated with overall lymphoma risk (multivariable-adjusted OR for highest versus lowest third = 0.77 [95% CI = 0.57-1.03], p

Indexed as

AdultAgedAged, 80 and overCase-Control StudiesEuropeFemaleFollow-Up StudiesHumansInsulin-Like Growth Factor ILymphomaMaleMiddle AgedNutrition SurveysOdds RatioRiskRisk FactorsInsulin-Like Growth Factor IEPIC cohortIGF-Ilymphomanested case-controlnon-Hodgkin lymphomaplasmaprospective

Identifiers

PMID27870006
PMCPMC5299544
OpenAlexW2556507705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.