Evidence map›Paper›PMID 27869748›Full record

ArticleInternational journal of molecular sciences2016

Design of New Antibacterial Enhancers Based on AcrB's Structure and the Evaluation of Their Antibacterial Enhancement Activity.

Yi Song, Rongxin Qin, Xichun Pan, Qin Ouyang, Tianyu Liu, Zhaoxia Zhai, Yingchun Chen, Bin Li, Hong Zhou

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Medicinal Chemistry of Inhibitors Targeting Resistant Bacteria.Current topics in medicinal chemistry · 2022
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yi SongDepartment of Pharmacology, College of Pharmacy, The Third Military Medical University, Chongqing 400038, China. songyi19890126@163.com.
Rongxin QinDepartment of Pharmacology, College of Pharmacy, The Third Military Medical University, Chongqing 400038, China. michel_0415@163.com.
Xichun PanDepartment of Pharmacology, College of Pharmacy, The Third Military Medical University, Chongqing 400038, China. xichunpan@163.com.
Qin OuyangDepartment of Medicinal Chemistry, College of Pharmacy, The Third Military Medical University, Chongqing 400038, China. ouyangq@tmmu.edu.cn.
Tianyu LiuDepartment of Medicinal Chemistry, College of Pharmacy, The Third Military Medical University, Chongqing 400038, China. liutianyu@tmmu.edu.cn.
Zhaoxia ZhaiDepartment of Pharmacology, College of Pharmacy, The Third Military Medical University, Chongqing 400038, China. zzzhaoxia@sina.com.
Yingchun ChenDepartment of Medicinal Chemistry, College of Pharmacy, The Third Military Medical University, Chongqing 400038, China. ycchen@scu.edu.cn.
Bin LiDepartment of Pharmacology, College of Pharmacy, The Third Military Medical University, Chongqing 400038, China. libin6033@sina.com.
Hong ZhouDepartment of Pharmacology, College of Pharmacy, The Third Military Medical University, Chongqing 400038, China. zhouh64@163.com.
Army Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously, artesunate (AS) and dihydroartemisinine 7 (DHA7) were found to have antibacterial enhancement activity against

Indexed as

AnimalsAnti-Bacterial AgentsArtemisininsATP-Binding Cassette, Sub-Family C Proteinsbeta-LactamsCell LineCell SurvivalDose-Response Relationship, DrugDrug DesignDrug SynergismEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialMacrophagesMiceMicrobial Sensitivity TestsAcrB protein, E coliAnti-Bacterial AgentsArtemisininsartenimolATP-Binding Cassette, Sub-Family C Proteinsbeta-LactamsEscherichia coli ProteinsAcrB inhibitorantibacterial enhancerDHA27molecular mechanism

Identifiers

PMID27869748
PMCPMC5133929
OpenAlexW2552994968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.