ReviewMicroorganisms2016
EPS-Then and Now.
Review in Microorganisms, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
119 citing papers in PubMed.
- Biofilms on microplastics across ecological systems: Formation mechanisms, community composition, environmental impacts, and ecotoxicity.World journal of microbiology & biotechnology · 2026Review
- Substrate-driven phage community structure and phage-host dynamics in anaerobic digesters.Environmental microbiome · 2026Article
- Molecular rotors reveal the 3D viscous habitat of mucus-colonizing bacteria.Nature communications · 2026Article
- Article
- The Biofilm Plight in Healthcare: Orchestration and Control by Lactiplantibacillus plantarum.Probiotics and antimicrobial proteins · 2026Review
- Microbial Exopolysaccharides, Redox Modulation, and Antioxidant Activity in Fermented Foods.Antioxidants (Basel, Switzerland) · 2026Review
- Complementary functionalities of extracellular polymeric substances, adhesion ability and hydrophobicity in Pseudomonas isolates may help the selection of strategically advantageous microbial inoculants.World journal of microbiology & biotechnology · 2026Article
- Heterotrophic bacterial bioleaching and sequestration of uranium from mineral resources: a review.Frontiers in microbiology · 2026Review
- Extracellular polymeric substances as local nucleation microenvironments in ureolytic MICP for concrete crack sealing: a mini review.Frontiers in microbiology · 2026Review
- Pathogenic Characteristics of Shrimp Early Mortality Syndrome (EMS)-Causing Vibrio parahaemolyticus: A Comparative Transcriptomic Study Suggests the Relationship Between Metabolic Fitness and Virulence Gene Expression.Environmental microbiology reports · 2025Article
- Article
- Article
- Article
- Bioavailable Dissolved Organic Carbon Serves as a Key Regulator of Phosphorus Dynamics in Stream Biofilms.Environmental microbiology reports · 2025Article
- Constituent of extracellular polymeric substances (EPS) produced by a range of soil bacteria and fungi.BMC microbiology · 2025Article
- Copper induced augmentation of antibiotic resistance in Acinetobacter baumannii MCC 3114.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Biochemistry of Bacterial Biofilm: Insights into Antibiotic Resistance Mechanisms and Therapeutic Intervention.Life (Basel, Switzerland) · 2025Review
- Transcriptome analysis of calcium hydroxide tolerance inFrontiers in microbiology · 2025Article
- Linking microbial ecology to the cycling of neutral and acidic polysaccharides in pustular mats from Shark Bay, Western Australia.Frontiers in microbiology · 2025Article
- Biotechnology revival:Frontiers in microbiology · 2025Review
59 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
"Slime" played a brief and spectacular role in the 19th century founded by the theory of primordial slime by Ernst Haeckel. However, that substance was never found and eventually abandoned. Further scientific attention slowly began in the 1930s referring to slime as a microbial product and then was inspired by "How bacteria stick" by Costerton et al. in 1978, and the matrix material was considered to be polysaccharides. Later, it turned out that proteins, nucleic acids and lipids were major other constituents of the extracellular polymeric substances (EPS), an acronym which was highly discussed. The role of the EPS matrix turns out to be fundamental for biofilms, in terms of keeping cells in proximity and allowing for extended interaction, resource capture, mechanical strength and other properties, which emerge from the life of biofilm organisms, including enhanced tolerance to antimicrobials and other stress. The EPS components are extremely complex and dynamic and fulfil many functional roles, turning biofilms into the most ubiquitous and successful form of life on Earth.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.