Evidence map›Paper›PMID 27869295›Full record

ArticleBiotechnology and bioengineering2017

Noninvasive assessment of tissue-engineered graft viability by oxygen-17 magnetic resonance spectroscopy.

Samuel A Einstein, Bradley P Weegman, Jennifer P Kitzmann, Klearchos K Papas, Michael Garwood

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biotechnology and bioengineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Samuel A EinsteinCenter for Magnetic Resonance Research and Department of Radiology, University of Minnesota, 2021 Sixth Street SE, Minneapolis, Minnesota, 55455.
Bradley P WeegmanCenter for Magnetic Resonance Research and Department of Radiology, University of Minnesota, 2021 Sixth Street SE, Minneapolis, Minnesota, 55455.
Jennifer P KitzmannDepartment of Surgery, University of Arizona, Tucson, Arizona.
Klearchos K PapasDepartment of Surgery, University of Arizona, Tucson, Arizona.
Michael GarwoodCenter for Magnetic Resonance Research and Department of Radiology, University of Minnesota, 2021 Sixth Street SE, Minneapolis, Minnesota, 55455.
University of Minnesota · USUniversity of Arizona · US

Funding

NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
STUDY OF BRAIN OXIDATIVE METABOLISM BY 17-0 MRS IMAGINGR01NS041262 · NINDS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI CHEN, WEI · 2002 to 2011
$4.6M
Quantitative and Non-invasive Imaging of Oxygen Metabolism in Human BrainR01NS070839 · NINDS · UNIVERSITY OF MINNESOTA · PI ZHU, XIAO-HONG · 2010 to 2014
$2.2M
Ultra High Field (16.4 Tesla) Animal MRI/MRS SystemS10RR025031 · NCRR · UNIVERSITY OF MINNESOTA · PI GARWOOD, MICHAEL · 2008 to 2008
$2.0M
NCRR NIH HHS S10 RR025031NIBIB NIH HHS P41 EB015894NINDS NIH HHS R01 NS041262NINDS NIH HHS R01 NS070839
6 · The paper itself

Abstract

Transplantation of macroencapsulated tissue-engineered grafts (TEGs) is being investigated as a treatment for type 1 diabetes, but there is a critical need to measure TEG viability both in vitro and in vivo. Oxygen deficiency is the most critical issue preventing widespread implementation of TEG transplantation and delivery of supplemental oxygen (DSO) has been shown to enhance TEG survival and function in vivo. In this study, we demonstrate the first use of oxygen-17 magnetic resonance spectroscopy (

Indexed as

Bioartificial OrgansPancreas, ArtificialAnimalsCell LineGraft SurvivalMagnetic Resonance SpectroscopyMiceModels, BiologicalOxygen IsotopesTissue EngineeringOxygen Isotopesbioartificial pancreasmacroencapsulationmagnetic resonance spectroscopytissue-engineered graftviability assessment

Identifiers

PMID27869295
PMCPMC5459307
OpenAlexW2551354936

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.