ArticleScientific reports2016
Motor noise is rich signal in autism research and pharmacological treatments.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- An examination of active inference in autistic adults using immersive virtual reality.Scientific reports · 2021Trial
- Motor Disorders in Autism: From Comorbidity to Core Criterion.Autism research : official journal of the International Society for Autism Research · 2026Review
- The relationship between speed and curvature differs in autistic and non-autistic tracing movements.Scientific reports · 2026Article
- Mismatching Expressions: Spatiotemporal and Kinematic Differences in Autistic and Non-Autistic Facial Expressions.Autism research : official journal of the International Society for Autism Research · 2026Article
- Commentary: Exploring the clinical features of minimally verbal autistic children.Frontiers in psychiatry · 2026Article
- Facial micro-movements as a proxy of increasingly erratic heart rate variability while experiencing pressure pain.Frontiers in neuroscience · 2026Article
- Multimodal evidence and technology-enabled accommodations for autistic adults: an evidential framework for autism research and practice.Frontiers in psychiatry · 2026Article
- The Neuroimmunology of Autism.Molecular neurobiology · 2025Review
- Motor organisation of social play in children with autism.Journal of the Royal Society, Interface · 2025Article
- Setting Up Our Lab-in-a-Box: Paving the Road Towards Remote Data Collection for Scalable Personalized Biometrics.Journal of personalized medicine · 2025Article
- Application of White Noise in Minors with Autism Spectrum Disorder.Behavioral sciences (Basel, Switzerland) · 2025Article
- Effective Autism Classification Through Grasping Kinematics.Autism research : official journal of the International Society for Autism Research · 2025Article
- Hidden social and emotional competencies in autism spectrum disorders captured through the digital lens.Frontiers in psychiatry · 2025Article
- Common Critiques and Recommendations for Studies in Neurology Using Machine Learning Methods.Neurology · 2024Article
- Theoretical-Methodological Foundations for the Global Integration Method (Método de Integração Global-MIG) in the Treatment of Autism Spectrum Disorder.Children (Basel, Switzerland) · 2024Review
- Digital screener of socio-motor agency balancing motor autonomy and motor control.Frontiers in human neuroscience · 2024Article
- Investigating the impact of motion in the scanner on brain age predictions.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Quantifying MR head motion in the Rhineland Study - A robust method for population cohorts.NeuroImage · 2023Article
- The time is ripe for the renaissance of autism treatments: evidence from clinical practitioners.Frontiers in integrative neuroscience · 2023Article
- Perceptual decision-making in autism as assessed by "spot the difference" visual cognition tasks.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human body is in constant motion, from every breath that we take, to every visibly purposeful action that we perform. Remaining completely still on command is a major achievement as involuntary fluctuations in our motions are difficult to keep under control. Here we examine the noise-to-signal ratio of micro-movements present in time-series of head motions extracted from resting-state functional magnetic resonance imaging scans in 1048 participants. These included individuals with autism spectrum disorders (ASD) and healthy-controls in shared data from the Autism Brain Imaging Data Exchange (ABIDE) and the Attention-Deficit Hyperactivity Disorder (ADHD-200) databases. We find excess noise and randomness in the ASD cases, suggesting an uncertain motor-feedback signal. A power-law emerged describing an orderly relation between the dispersion and shape of the probability distribution functions best describing the stochastic properties under consideration with respect to intelligence quotient (IQ-scores). In ASD, deleterious patterns of noise are consistently exacerbated with the presence of secondary (comorbid) neuropsychiatric diagnoses, lower verbal and performance intelligence, and autism severity. Importantly, such patterns in ASD are present whether or not the participant takes psychotropic medication. These data unambiguously establish specific noise-to-signal levels of head micro-movements as a biologically informed core feature of ASD.
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