Evidence map›Paper›PMID 27868062›Full record

SynthesisBioMed research international2016

Apolipoprotein E Gene Variants and Risk of Coronary Heart Disease: A Meta-Analysis.

Min Xu, Jun Zhao, Yu Zhang, Xu Ma, Qiaoyun Dai, Hong Zhi, Bei Wang, Lina Wang

Open access · hybridAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Role of Hyperlipidemia-RelatedMolecular syndromology · 2026
    Article
  8. Article
  9. Review
  10. Interplay Between 3D Chromatin Architecture and Gene Regulation at theInternational journal of molecular sciences · 2025
    Article
  11. Article
  12. Correlation ofWorld journal of cardiology · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. SR-B1-/-ApoE-R61h/h Mice Mimic Human Coronary Heart Disease.Cardiovascular drugs and therapy · 2024
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Min XuKey Laboratory of Environmental Medicine Engineering, Ministry of Education, Department of Epidemiology and Biostatistics, School of Public Health, Southeast University, Nanjing, China.ORCID 0000-0002-5265-3711
Jun ZhaoGraduate School of Peking Union Medical College, Beijing, China; National Research Institute for Family Planning, Beijing, China.
Yu ZhangCenters for Disease Control and Prevention, Zhejiang, China.
Xu MaGraduate School of Peking Union Medical College, Beijing, China; National Research Institute for Family Planning, Beijing, China.
Qiaoyun DaiNational Research Institute for Family Planning, Beijing, China.
Hong ZhiDepartment of Cardiology, ZhongDa Hospital, Southeast University, Nanjing, Jiangsu, China.
Bei WangKey Laboratory of Environmental Medicine Engineering, Ministry of Education, Department of Epidemiology and Biostatistics, School of Public Health, Southeast University, Nanjing, China.
Lina WangKey Laboratory of Environmental Medicine Engineering, Ministry of Education, Department of Epidemiology and Biostatistics, School of Public Health, Southeast University, Nanjing, China.ORCID 0000-0003-3665-5706
Southeast University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNTianjin Municipal Research Institute for Family Planning · CNZhejiang Center for Disease Control and Prevention · CNZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Apolipoproteins ECoronary Artery DiseaseGenetic MarkersGenetic Predisposition to DiseaseGenetic VariationHumansPolymorphism, Single NucleotidePrevalenceRisk FactorsApolipoproteins EGenetic Markers

Identifiers

PMID27868062
PMCPMC5102878
OpenAlexW2546316316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.