Enterocyte progenitors can dedifferentiate to replace lost Lgr5

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed.

1. BART-spatial unravels biologically significant transcriptional regulators from spatial omics data.bioRxiv : the preprint server for biology · 2026
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2. Intestinal organoid screen reveals that Bacillus velezensis PGM541 promotes epithelial proliferation via its metabolite butyric acid.Microbiome · 2026
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3. Molecular and Chromatin Accessibility Programs Underlying Epithelial Injury and Impaired Regeneration in Neonatal Necrotizing Enterocolitis.Cellular and molecular gastroenterology and hepatology · 2026
   Article
4. Changes in progenitors and differentiated epithelial cells of neonatal piglets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022
   Article
5. Telocytes: An Emerging Component of Stem Cell Niche Microenvironment.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2021
   Review
6. Identifying key regulators of the intestinal stem cell niche.Biochemical Society transactions · 2021
   Review
7. Classes of Drugs that Mitigate Radiation Syndromes.Frontiers in pharmacology · 2021
   Article
8. The cellular niche for intestinal stem cells: a team effort.Cell regeneration (London, England) · 2021
   Review
9. 1-(4-nitrobenzenesulfonyl)-4-penylpiperazine increases the number of Peyer's patch-associated regenerating crypts in the small intestines after radiation injury.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2019
   Article

Corrections and comments

• Comment on
  Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.2016

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.