Evidence map›Paper›PMID 27867912›Full record

ReviewBrain tumor research and treatment2016

Central Neurocytoma: A Review of Clinical Management and Histopathologic Features.

Seung J Lee, Timothy T Bui, Cheng Hao Jacky Chen, Carlito Lagman, Lawrance K Chung, Sabrin Sidhu, David J Seo, William H Yong, Todd L Siegal, Minsu Kim and 1 more

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Brain tumor research and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Invasive sellar extraventricular neurocytoma: illustrative case.Journal of neurosurgery. Case lessons · 2026
    Article
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  10. Review
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Seung J LeeDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.
Timothy T BuiDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.
Cheng Hao Jacky ChenDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.
Carlito LagmanDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.
Lawrance K ChungDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.
Sabrin SidhuDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.
David J SeoDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.
William H YongDepartment of Pathology & Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Todd L SiegalDepartment of Radiology, Division of Neuroradiology, Cooper University Hospital, Camden, NJ, USA.
Minsu KimDepartment of Neurosurgery, Yeungnam University College of Medicine, Daegu, Korea.
Isaac YangDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.
University of California, Los Angeles · USCooper University Hospital · USYeungnam University College

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central neurocytoma (CN) is a rare, benign brain tumor often located in the lateral ventricles. CN may cause obstructive hydrocephalus and manifest as signs of increased intracranial pressure. The goal of treatment for CN is a gross total resection (GTR), which often yields excellent prognosis with a very high rate of tumor control and survival. Adjuvant radiosurgery and radiotherapy may be considered to improve tumor control when GTR cannot be achieved. Chemotherapy is also not considered a primary treatment, but has been used as a salvage therapy. The radiological features of CN are indistinguishable from those of other brain tumors; therefore, many histological markers, such as synaptophysin, can be very useful for diagnosing CNs. Furthermore, the MIB-1 Labeling Index seems to be correlated with the prognosis of CN. We also discuss oncogenes associated with these elusive tumors. Further studies may improve our ability to accurately diagnose CNs and to design the optimal treatment regimens for patients with CNs.

Indexed as

Central neurocytomaHistopathologyManagement

Identifiers

PMID27867912
PMCPMC5114192
OpenAlexW2550404937

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.