Evidence map›Paper›PMID 27867756›Full record

ArticleTranslational vision science & technology2016

Reference Clinical Database for Fixation Stability Metrics in Normal Subjects Measured with the MAIA Microperimeter.

Marco U Morales, Saker Saker, Craig Wilde, Carlo Pellizzari, Aristophanes Pallikaris, Neil Notaroberto, Martin Rubinstein, Chiara Rui, Paolo Limoli, Michael K Smolek and 1 more

Abstract read
In one paragraph

Article in Translational vision science & technology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. An Analysis of Scotopic Microperimetry in Healthy Adults.Translational vision science & technology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Assessment ofBiomedicines · 2025
    Article
  16. Article
  17. Exploring Scotopic Microperimetry as an Outcome Measure in Choroideremia.Translational vision science & technology · 2024
    Article
  18. Foveolar Drusen Decrease Fixation Stability in Pre-Symptomatic AMD.Investigative ophthalmology & visual science · 2024
    Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marco U MoralesDivision of Clinical Neurosciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
Saker SakerDivision of Clinical Neurosciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
Craig WildeDivision of Clinical Neurosciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
Carlo PellizzariCentervue, Padua, Italy.
Aristophanes PallikarisInstitute of Vision and Optics, Department of Medicine, University of Crete, Heraklion, Greece.
Neil NotarobertoCLEVER Eye Institute, Slidell, LA, USA.
Martin RubinsteinDivision of Clinical Neurosciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
Chiara RuiCentervue, Padua, Italy.
Paolo LimoliCentro Studi Ipovisione, Milan, Italy.
Michael K SmolekVision Protection & Performance Division, USAARL, Fort Rucker, AL, USA.
Winfried M AmoakuDivision of Clinical Neurosciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to establish a normal reference database for fixation stability measured with the bivariate contour ellipse area (BCEA) in the Macular Integrity Assessment (MAIA) microperimeter.

methodsSubjects were 358 healthy volunteers who had the MAIA examination. Fixation stability was assessed using two BCEA fixation indices (63% and 95% proportional values) and the percentage of fixation points within 1° and 2° from the fovea (P1 and P2). Statistical analysis was performed with linear regression and Pearson's product moment correlation coefficient.

resultsAverage areas of 0.80 deg

conclusionsThe single parameter of the BCEA@95% may be taken as accurately reporting fixation stability and serves as a reference database of normal subjects with a cutoff area of 2.40 ± 2.04 deg TRANSLATIONAL RELEVANCE: Fixation stability can be measured with different indices. This study originates reference fixation values for the MAIA using a single fixation index.

Indexed as

BCEAfixationmicroperimetrynormal

Identifiers

PMID27867756
PMCPMC5113982

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.