Evidence map›Paper›PMID 27867716›Full record

ArticleBiomedical optics express2016

Automatic classification of atherosclerotic plaques imaged with intravascular OCT.

Jose J Rico-Jimenez, Daniel U Campos-Delgado, Martin Villiger, Kenichiro Otsuka, Brett E Bouma, Javier A Jo

Abstract read
In one paragraph

Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Histology-Grounded Automated Plaque Subtype Segmentation in Intravascular Optical Coherence Tomography.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Artificial Intelligence in Intracoronary Imaging.Current cardiology reports · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. AI-AssistedClinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jose J Rico-JimenezDepartment of Biomedical Engineering, Texas A & M University, College Station, TX, USA.
Daniel U Campos-DelgadoFacultad de Ciencias, Universidad Autonoma de San Luis Potosi, SLP, Mexico.
Martin VilligerWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA.
Kenichiro OtsukaWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA.
Brett E BoumaWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA.
Javier A JoDepartment of Biomedical Engineering, Texas A & M University, College Station, TX, USA.

Funding

TRD3: Percutaneous and Interstitial ImagingP41EB015903 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Brett E Bouma · 2012 to 2026
$22.4M
Morphological and Molecular Imaging System for in vivo Atherosclerosis ResearchR01HL111361 · NHLBI · TEXAS ENGINEERING EXPERIMENT STATION · PI APPLEGATE, BRIAN E. · 2012 to 2016
$1.7M
NHLBI NIH HHS R01 HL111361NIBIB NIH HHS P41 EB015903
6 · The paper itself

Abstract

Intravascular optical coherence tomography (IV-OCT) allows evaluation of atherosclerotic plaques; however, plaque characterization is performed by visual assessment and requires a trained expert for interpretation of the large data sets. Here, we present a novel computational method for automated IV-OCT plaque characterization. This method is based on the modeling of each A-line of an IV-OCT data set as a linear combination of a number of depth profiles. After estimating these depth profiles by means of an alternating least square optimization strategy, they are automatically classified to predefined tissue types based on their morphological characteristics. The performance of our proposed method was evaluated with IV-OCT scans of cadaveric human coronary arteries and corresponding tissue histopathology. Our results suggest that this methodology allows automated identification of fibrotic and lipid-containing plaques. Moreover, this novel computational method has the potential to enable high throughput atherosclerotic plaque characterization.

Indexed as

(100.2960) Image analysis(100.5010) Pattern recognition(170.3880) Medical and biological imaging(170.4500) Optical coherence tomography(170.6935) Tissue characterization

Identifiers

PMID27867716
PMCPMC5102521

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.