ArticleBiomedical optics express2016
Enhancement of image quality and imaging depth with Airy light-sheet microscopy in cleared and non-cleared neural tissue.
Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 60 citations in OpenAlex.
- Polarization-engineered aberration-resilient light sheet microscopy.bioRxiv : the preprint server for biology · 2026Article
- A practical guide to light-sheet microscopy for nanoscale imaging: Looking beyond the cell.Journal of applied physics · 2024Article
- Bessel Beams in Ophthalmology: A Review.Micromachines · 2023Review
- Experimentally unsupervised deconvolution for light-sheet microscopy with propagation-invariant beams.Light, science & applications · 2022Article
- Theoretical Analysis of Airy-Gauss Bullets Obtained by Means of High Aperture Binary Micro Zonal Plate.Micromachines · 2022Article
- Light sheet based volume flow cytometry (VFC) for rapid volume reconstruction and parameter estimation on the go.Scientific reports · 2022Article
- Application of Airy beam light sheet microscopy to examine early neurodevelopmental structures in 3D hiPSC-derived human cortical spheroids.Molecular autism · 2021Article
- Light Sheet Illumination for 3D Single-Molecule Super-Resolution Imaging of Neuronal Synapses.Frontiers in synaptic neuroscience · 2021Review
- Selecting optimal spectral bands for improved detection of autofluorescent biomarkers in multiphoton microscopy.Journal of biomedical optics · 2020Article
- Light-Sheet Fluorescence Microscopy with Scanning Non-diffracting Beams.Scientific reports · 2020Article
- Multi-photon attenuation-compensated light-sheet fluorescence microscopy.Scientific reports · 2020Article
- SSPIM: a beam shaping toolbox for structured selective plane illumination microscopy.Scientific reports · 2018Article
- Light-sheet microscopy with attenuation-compensated propagation-invariant beams.Science advances · 2018Article
- Enhancement of image quality and imaging depth with Airy light-sheet microscopy in cleared and non-cleared neural tissue.Biomedical optics express · 2016Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have investigated the effect of Airy illumination on the image quality and depth penetration of digitally scanned light-sheet microscopy in turbid neural tissue. We used Fourier analysis of images acquired using Gaussian and Airy light-sheets to assess their respective image quality versus penetration into the tissue. We observed a three-fold average improvement in image quality at 50 μm depth with the Airy light-sheet. We also used optical clearing to tune the scattering properties of the tissue and found that the improvement when using an Airy light-sheet is greater in the presence of stronger sample-induced aberrations. Finally, we used homogeneous resolution probes in these tissues to quantify absolute depth penetration in cleared samples with each beam type. The Airy light-sheet method extended depth penetration by 30% compared to a Gaussian light-sheet.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.