ArticleAIDS research and treatment2016
Insights into Adherence among a Cohort of Adolescents Aged 12-20 Years in South Africa: Reported Barriers to Antiretroviral Treatment.
Article in AIDS research and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and predictors of loss to follow-up among adults on antiretroviral therapy in Ethiopia: a systematic review and meta-analysis of cohort studies.AIDS research and therapy · 2026Pooled it
- Demographic and Socioeconomic Factors Associated With ART Nonadherence Among 15 Years and Older South Africans. Evidence From the 2022 Cross-Sectional Population-Based Household Survey.AIDS research and treatment · 2026Article
- HIV Care Through Their Eyes: Navigating HIV Services and ART Adherence Among Adolescents and Their Caregivers in Lusaka, Zambia.AIDS research and treatment · 2026Article
- Perceptions of adolescents and young adults failing antiretroviral therapy on adherence in Gauteng, South Africa.Southern African journal of HIV medicine · 2026Article
- Age-specific all-cause mortality rates among adolescents and youth living with and without HIV: Evidence from a cohort study in South Africa.Journal of the International AIDS Society · 2025Article
- Disclosure and Experiences of HIV-Related Stigma among Adolescents and Young Adults Living with HIV in South Africa.AIDS and behavior · 2024Article
- Exploring Self-reported Adherence Measures to Screen for Elevated HIV Viral Load in Adolescents: A South African Cohort Study.AIDS and behavior · 2023Article
- Risk factors for interruption in treatment among HIV-infected adolescence attending health care and treatment clinics in Tanzania.AIDS research and therapy · 2023Article
- Article
- Presence of Teen Clubs and its Association with Clinic Attendance among Adolescents Living with HIV in Tanzania: A Retrospective Cohort Study.The East African health research journal · 2023Article
- Two years after lockdown: reviewing the effects of COVID-19 on health services and support for adolescents living with HIV in South Africa.Journal of the International AIDS Society · 2022Article
- Factors associated with antiretroviral therapy adherence among adolescents living with HIV in the era of isoniazid preventive therapy as part of HIV care.PLOS global public health · 2022Article
- Predictors of loss to follow up from antiretroviral therapy among adolescents with HIV/AIDS in Tanzania.PloS one · 2022Article
- Uncovering ART adherence inconsistencies: An assessment of sustained adherence among adolescents in South Africa.Journal of the International AIDS Society · 2021Article
- Social Networks and Barriers to ART Adherence Among Young Adults (18-24 years) Living with HIV at Selected Primary Health Facilities of South-Western Uganda: A Qualitative Study.HIV/AIDS (Auckland, N.Z.) · 2021Article
- Perceived barriers to the uptake of health services among first-year university students in Johannesburg, South Africa.PloS one · 2021Article
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- Article
- Article
- The Complexities of Antiretroviral Treatment Adherence Among Adolescents and Young Adults in South Africa: Insights From a Scoping Review.Journal of the International Association of Providers of AIDS CareReview
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Adolescents experience disproportionately high rates of poor ART outcomes compared to adults despite prolonged use of antiretroviral therapy in Southern African treatment programs, presenting a significant challenge to national attempts to meet the UNAIDS 90-90-90 targets for 2020. This cohort study among adolescents aged 12-20 years accessing ART care at two urban public-sector clinics in Johannesburg between September and November 2013 aimed to identify factors potentially associated with poor attendance at clinic visits. Patients were followed up through routine medical records to identify missed visits (failing to attend clinic within 30 days of scheduled visit date) up to 2 years after enrolment. We enrolled 126 adolescents on ART for a median of 6.3 years (IQR: 2.7-8.4). A total of 47 (38%) adolescents missed a scheduled visit within 24 months of enrolment. Older adolescents (18-20 years) were more likely to miss a visit compared to adolescents aged 12-14 years (risk ratio (RR) = 1.72; 95% CI: 1.00-2.95). Those who were identified to have difficulty in taking medication (RR = 1.57; 95% CI: 1.13-2.18) as a barrier to care were more likely to miss a visit compared to adolescents who did not. Awareness of treatment fatigue, challenges to taking ART, and caregiver difficulties is important when considering interventions to improve treatment outcomes among adolescents.
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Registered trials
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