Evidence map›Paper›PMID 27867655›Full record

ArticleJournal of thoracic disease2016

Veno-arterial extracorporeal membrane oxygenation (VA ECMO) in postcardiotomy cardiogenic shock: how much pump flow is enough?

Federico Pappalardo, Andrea Montisci

Abstract readComment
In one paragraph

Article in Journal of thoracic disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Structured review of post-cardiotomy extracorporeal membrane oxygenation: part 1-Adult patients.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Federico PappalardoDepartment of Anesthesia and Intensive Care, San Raffaele Scientific Institute, Milan, Italy.
Andrea MontisciDepartment of Anesthesia and Intensive Care, Sant'Ambrogio Clinical Institute, San Donato Hospital Group, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-cardiotomy cardiogenic shock (PCCS) is a complication of heart surgery associated with a poor prognosis: veno-arterial extracorporeal membrane oxygenation (VA ECMO) ensures end-organ perfusion while fully replacing heart and lung function, though it is associated with unsatisfactory results. Few studies have identified reliable predictors of poor prognosis early in the course of extracorporeal support. A recent study showed the strong prognostic power of urine output in the first 24 hours of VA ECMO in predicting early and late mortality of PCCS. Urine output is a commonly collected parameter in all intensive care units (ICU) and has a defined role in the diagnosis of acute kidney injury (AKI) and is inexpensive. These findings offer the possibility to summarize some aspects regarding the adequacy of extracorporeal support early in the course of cardiogenic shock and to shed light about cardio-renal interactions in ECMO patients. Finally, it is our opinion that a timely implantation of mechanical circulatory support in post cardiotomy shock should be considered if systemic perfusion is not ensured by low or medium dose inotropic support and intra-aortic balloon counterpulsation.

Indexed as

cardiac surgerycardiogenic shockExtracorporeal membrane oxygenation (ECMO)multiple organ failure

Identifiers

PMID27867655
PMCPMC5107499

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.