ReviewESC heart failure2016
Obesity paradox in heart failure: a heavy matter.
Review in ESC heart failure, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Clinical significance of nutritional status in patients with chronic heart failure-a systematic review.Heart failure reviews · 2019Pooled it
- Pro-gastrin-releasing peptide and outcome in patients with heart failure and anaemia: results from the RED-HF study.ESC heart failure · 2018Trial
- Body Mass Index, Clinical Outcomes, and Mortality in Heart Failure: A Mendelian Randomization Study.Journal of the American College of Cardiology · 2026Article
- The creatinine-to-body weight ratio predicts mortality in critically ill patients with heart failure: a retrospective cohort study of the MIMIC-IV database.BMC cardiovascular disorders · 2026Article
- Efficacy and safety of levosimendan in acute heart failure patients with different body mass index: a multicenter, retrospective, observational real-world study.Frontiers in cardiovascular medicine · 2026Article
- The continuum of prevention and heart failure in cardiovascular medicine: A joint scientific statement from the Heart Failure Society of America and the American Society for Preventive Cardiology.American journal of preventive cardiology · 2025Review
- Potential Implications of Body Mass Composition Changes in Heart Failure Patients in the Era of SGLT2i, GLP-1 RA, and GIP/GLP-1 RA.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Parental obesity predisposes male and female offspring to exacerbated cardiac dysfunction and increased mortality after myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2025Article
- Association of visceral adiposity index (VAI) with prognosis in patients with metabolic syndrome and heart failure with reduced ejection fraction.BMC cardiovascular disorders · 2025Article
- Prognostic implication of sarcopenia diagnosed by updated Asian Working Group for Sarcopenia criteria in older patients with heart failure: Utility and limitation.The journal of nutrition, health & aging · 2025Article
- Obesity: the perfect storm for heart failure.ESC heart failure · 2024Review
- Physical Activity, Cardiorespiratory Fitness, and the Obesity Paradox with Consideration for Racial and/or Ethnic Differences: A Broad Review and Call to Action.Reviews in cardiovascular medicine · 2024Review
- Cardiometabolic Phenotyping in Heart Failure: Differences between Patients with Reduced vs. Preserved Ejection Fraction.Diagnostics (Basel, Switzerland) · 2023Article
- Obesity Paradox among Heart Failure with Reduced Ejection Fraction Patients: A Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2022Article
- Characteristics and outcomes of patients admitted for acute heart failure in a single-centre study.ESC heart failure · 2022Article
- Heart Failure Patients and Implications of Obesity: A Single-Center Retrospective Study.Cureus · 2021Article
- Caution, "normal" BMI: health risks associated with potentially masked individual underweight-EPMA Position Paper 2021.The EPMA journal · 2021Article
- Energy intake during hospital stay predicts all-cause mortality after discharge independently of nutritional status in elderly heart failure patients.Clinical research in cardiology : official journal of the German Cardiac Society · 2021Observational
- High percent body fat mass predicts lower risk of cardiac events in patients with heart failure: an explanation of the obesity paradox.BMC geriatrics · 2021Article
- The association of non-alcoholic fatty liver disease and cardiac structure and function-Framingham Heart Study.Liver international : official journal of the International Association for the Study of the Liver · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity and heart failure are two of the leading causes of morbidity and mortality in the world. The relationship between obesity and cardiovascular diseases is complex and not fully understood. While the risk of developing heart failure has been shown to be higher in patients who are obese, there is a survival advantage for obese and overweight patients compared with normal weight or low weight patients. This phenomenon was first described by Horwich
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.