Evidence map›Paper›PMID 27867469›Full record

ArticleMedical gas research

Hyperbaric oxygen increases tissue-plasminogen activator-induced thrombolysis

Laurent Chazalviel, Benoit Haelewyn, Mickael Degoulet, Jean-Eric Blatteau, Nicolas Vallée, Jean-Jacques Risso, Stéphane Besnard, Jacques H Abraini

Open access · greenAbstract read
In one paragraph

Article in Medical gas research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Effects of normobaricMedical gas research
    Article
  10. Review
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Laurent ChazalvielUniversité de Caen Normandie - CNRS, UMR 6301 ISTCT, Equipe Cervoxy, Caen, France.
Benoit HaelewynUniversité de Caen Normandie, CURB, Caen, France.
Mickael DegouletUniversité de Caen Normandie, Faculté de Médecine, France.
Jean-Eric BlatteauHôpital d'Instruction des Armées (HIA) Sainte-Anne, Service de Médecine Hyperbare et Expertise Plongée (SMHEP), Toulon, France.
Nicolas ValléeInstitut de Recherche Biomédicale des Armées (IRBA), Equipe Résidente de Recherche Subaquatique Opérationnelle (ERRSO), Toulon, France.
Jean-Jacques RissoInstitut de Recherche Biomédicale des Armées (IRBA), Equipe Résidente de Recherche Subaquatique Opérationnelle (ERRSO), Toulon, France.
Stéphane BesnardUniversité de Caen Normandie - INSERM, UMR 1075, Caen, France.
Jacques H AbrainiUniversité de Caen Normandie, Faculté de Médecine, France; Institut de Recherche Biomédicale des Armées (IRBA), Equipe Résidente de Recherche Subaquatique Opérationnelle (ERRSO), Toulon, France; Université Laval, Département d'Anesthésiologie, Québec, Canada.ORCID 0000-0002-6435-9819
Université de Caen Normandie · FRHôpital d'Instruction des Armées Sainte-Anne · FRNormandie Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent data have shown that normobaric oxygen (NBO) increases the catalytic and thrombolytic efficiency of recombinant tissue plasminogen activator (rtPA)

Indexed as

brain edemabrain ischemiahyperbaric oxygenin vitroratstrokethrombolysistissue-plasminogen activator

Identifiers

PMID27867469
PMCPMC5110134
OpenAlexW2464676154

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.