Evidence map›Paper›PMID 27867396›Full record

ReviewInternational journal of endocrinology2016

Challenges in the Diagnosis and Management of Growth Hormone Deficiency in India.

Mathew John, Ekaterina Koledova, Kanakatte Mylariah Prasanna Kumar, Harshal Chaudhari

Open access · goldAbstract readReview
In one paragraph

Review in International journal of endocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Effects ofNutrients · 2026
    Trial
  2. Article
  3. Patient preferences for growth hormone treatment in Japanese children.Pediatrics international : official journal of the Japan Pediatric Society · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Mathew JohnProvidence Endocrine and Diabetes Specialty Centre, Thiruvananthapuram, Kerala, India.
Ekaterina KoledovaLead Endocrinology, Global Medical, Safety and CMO, Merck, Darmstadt, Germany.
Kanakatte Mylariah Prasanna KumarCentre for Diabetes and Endocrine Care, Bangalore, Karnataka, India.
Harshal ChaudhariBiopharma, NDD and Endocrinology, Merck Specialties Pvt. Ltd., Mumbai, India.ORCID 0000-0001-5542-7544
Bangalore Diabetes Centre · INMerck (Germany) · DEMerck (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In clinical practice, every year approximately 150,000 children are referred with short stature (SS) based on a cut-off of fifth percentile. The most important endocrine and treatable cause of SS is growth hormone deficiency (GHD). The lack of reliable data on the prevalence of GHD in India limits estimation of the magnitude of this problem. The diagnosis and treatment of GHD are hurdled with various challenges, restricting the availability of growth hormone (GH) therapy to only a very limited segment of the children in India. This review will firstly summarize the gaps and challenges in diagnosis and treatment of GHD based on literature analysis. Subsequently, it presents suggestions from the members at advisory board meetings to overcome these challenges. The advisory board suggested that early initiation of the therapy could better the chances of achieving final adult height within the normal range for the population. Education and awareness about growth disorders among parents, regular training for physicians, and more emphasis on using the Indian growth charts for growth monitoring would help improve the diagnosis and treatment of children with GHD. Availability of an easy-to-use therapy delivery system could also be beneficial in improving adherence and achieving satisfactory outcomes.

Identifiers

PMID27867396
PMCPMC5102730
OpenAlexW2541420529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.