Evidence map›Paper›PMID 27867298›Full record

ArticleBreast cancer : basic and clinical research2016

Prophylactic Bilateral Nipple-sparing Mastectomy and a Staged Breast Reconstruction Technique: Preliminary Results.

Thierry Tondu, Filip Thiessen, Wiebren A A Tjalma

Abstract read
In one paragraph

Article in Breast cancer : basic and clinical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Prophylactic Surgery: For Whom, When and How?Breast care (Basel, Switzerland) · 2017
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thierry TonduMultidisciplinary Breast Clinic-Unit of Gynecologic Oncology, Antwerp University Hospital, University of Antwerp, Antwerpen, Belgium.; Plastic Surgery Unit, Antwerp University Hospital, Antwerpen, Belgium.
Filip ThiessenMultidisciplinary Breast Clinic-Unit of Gynecologic Oncology, Antwerp University Hospital, University of Antwerp, Antwerpen, Belgium.; Plastic Surgery Unit, Antwerp University Hospital, Antwerpen, Belgium.
Wiebren A A TjalmaMultidisciplinary Breast Clinic-Unit of Gynecologic Oncology, Antwerp University Hospital, University of Antwerp, Antwerpen, Belgium.; Department of Obstetrics and Gynecology, Antwerp University Hospital, University of Antwerp, Antwerpen, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

More high-risk women with breast cancer are identified using genetic testing at a younger age. These young women often opt for prophylactic surgery. Most patients are reluctant for extra donor-site scars besides infections and necrosis. In order to reduce these risks, a two-stage breast reconstruction technique is used for high-risk women with large or ptotic breasts. We presume that this procedure will reduce the risk of skin envelope and nipple-areola complex (NAC) necrosis to less than 1%. In the first stage, an inferior pedicle reduction is performed to obtain large volume reduction with maximal safety for the NAC. The ptosis, skin excess, and malpositioning of the NAC are corrected safely at this stage. In the second stage, the skin-sparing mastectomy is performed with or without nipple sparing. During this procedure, the areola is never removed. A bilateral breast reconstruction is then performed with an immediate subpectoral prothesis or delayed with the use of a subpectoral tissue expander. In this way, we aim to meet the patient's wish to undergo bilateral risk reducing mastectomy in breasts that need ptosis correction without donor-site scarring. This article describes the procedure and reports the preliminary data.

Indexed as

BRCAhigh riskinfectionmastectomynecrosisnipple sparingprophylacticreconstruction

Identifiers

PMID27867298
PMCPMC5104285

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.