Evidence map›Paper›PMID 27867276›Full record

ArticlePharmacognosy magazine

Ursolic Acid, a Natural Pentacylcic Triterpene from

Rola M Labib, Sherif S Ebada, Fadia S Youssef, Mohamed L Ashour, Samir A Ross

Open access · greenAbstract read
In one paragraph

Article in Pharmacognosy magazine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. The Role ofMolecules (Basel, Switzerland) · 2022
    Article
  8. Plant Terpenoids as Hit Compounds against Trypanosomiasis.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rola M LabibDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt; National Center for Natural Products Research, MS, USA.
Sherif S EbadaDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Fadia S YoussefDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Mohamed L AshourDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Samir A RossNational Center for Natural Products Research, MS, USA; Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, University, MS, USA.
Ain Shams University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeishmaniasis and African trypanosomiasis are recognized as the leading causes of mortality and morbidity with the greatest prevalence in the developing countries. They affect more than one billion of the poorest people on the globe.

objectiveTo find a cheap, affordable, safe, and efficacious antileshmanial and antitrypanosomal natural drug and to elucidate its probable mode of action. MATERIALS AND

methodsPhytochemical investigation of the non-polar fraction of the methanol extract of leaves of

resultsUrsolic acid displayed considerable antitrypanosomal and antileishmanial activities with IC

conclusionUrsolic acid offers a safe, effective and cheap antitrypanosomal and antileishmanial candidate acting on several key parasitic enzymes. SUMMARY: The fresh leaves of

Indexed as

AntileishmanialantitrypanosomalOchrosia ellipticaursolic acidvirtual screening

Identifiers

PMID27867276
PMCPMC5096280
OpenAlexW2549453913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.