Evidence map›Paper›PMID 27867265›Full record

ArticlePharmacognosy magazine

Alpha-glucosidase Inhibitory and Antioxidant Potential of Antidiabetic Herb

Tsun-Thai Chai, Chee-Siong Khoo, Chong-Siang Tee, Fai-Chu Wong

Open access · greenAbstract read
In one paragraph

Article in Pharmacognosy magazine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. The GenusFrontiers in pharmacology · 2022
    Review
  4. Article
  5. Antihyperglycemic Activity ofPharmacognosy magazine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tsun-Thai ChaiCentre for Biodiversity Research, Universiti Tunku Abdul Rahman, Kampar, Malaysia; Department of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar, Malaysia.
Chee-Siong KhooDepartment of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar, Malaysia.
Chong-Siang TeeCentre for Biodiversity Research, Universiti Tunku Abdul Rahman, Kampar, Malaysia; Department of Biological Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar, Malaysia.
Fai-Chu WongCentre for Biodiversity Research, Universiti Tunku Abdul Rahman, Kampar, Malaysia; Department of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar, Malaysia.
Universiti Tunku Abdul Rahman · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

objectiveThis study aimed to investigate the antiglucosidase and antioxidant activity of solvent fractions of MATERIALS AND

methodsLeaf and callus methanol extracts were fractionated to produce hexane, chloroform, ethyl acetate, butanol, and water fractions. Antiglucosidase and 1,1-diphenyl-2-picrylhydrazyl scavenging activities as well as total phenolic (TP), total flavonoid (TF), and total coumarin (TC) contents were evaluated. Lineweaver-Burk plot analysis was performed on leaf and callus fractions with the strongest antiglucosidase activity.

resultsLeaf ethyl acetate fraction (LEF) had the strongest antiglucosidase (EC

conclusionLEF had potent antiglucosidase activity and concurrent antioxidant activity. CEF had the highest antiglucosidase activity among all fractions. Callus culture is a promising tool for enhancing production of potent α-glucosidase inhibitors. SUMMARY: Leaf ethyl acetate fraction (LEF) had the strongest antiglucosidase (EC

Indexed as

Alternanthera sessilisantiglucosidaseantioxidantcallusleaf

Identifiers

PMID27867265
PMCPMC5096269
OpenAlexW2553767246

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.