Evidence map›Paper›PMID 27867198›Full record

ReviewNature reviews. Microbiology2017

Probing the evolution, ecology and physiology of marine protists using transcriptomics.

David A Caron, Harriet Alexander, Andrew E Allen, John M Archibald, E Virginia Armbrust, Charles Bachy, Callum J Bell, Arvind Bharti, Sonya T Dyhrman, Stephanie M Guida and 5 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 231 citations in OpenAlex.

  1. Magnetotaxis in an anaerobic ciliate via tripartite syntrophy.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  4. A genomic view of Earth's biomes.Nature reviews. Genetics · 2026
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 2 countries.

David A CaronDepartment of Biological Sciences, University of Southern California, 3616 Trousdale Parkway, Los Angeles, California 90089, USA.
Harriet AlexanderDepartment of Population Health and Reproduction, School of Veterinary Medicine, 1 Shields Avenue, University of California Davis, Davis, California 95616, USA.
Andrew E AllenMicrobial and Environmental Genomics, J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, San Diego, California 92037, USA.
John M ArchibaldDepartment of Biochemistry and Molecular Biology, Dalhousie University, Sir Charles Tupper Medical Building, 5850 College Street, Halifax, Nova Scotia B3H 4R2, Canada.
E Virginia ArmbrustSchool of Oceanography, University of Washington, 1503 NE Boat Street, Seattle, Washington 98195, USA.
Charles BachyMonterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, California 95039, USA.
Callum J BellNational Center for Genome Resources, 2935 Rodeo Park Drive East, Santa Fe, New Mexico 87505, USA.
Arvind BhartiSyngenta Biotechnology, 629 Davis Drive, Research Triangle Park, North Carolina 27709, USA.
Sonya T DyhrmanDepartment of Earth and Environmental Sciences and the Lamont-Doherty Earth Observatory, Columbia University, 61 Route 9W, Palisades, New York 10964, USA.
Stephanie M GuidaNational Center for Genome Resources, 2935 Rodeo Park Drive East, Santa Fe, New Mexico 87505, USA.
Karla B HeidelbergDepartment of Biological Sciences, University of Southern California, 3616 Trousdale Parkway, Los Angeles, California 90089, USA.
Jonathan Z KayeGordon and Betty Moore Foundation, 1661 Page Mill Road, Palo Alto, California 94304, USA.
Julia MetznerGordon and Betty Moore Foundation, 1661 Page Mill Road, Palo Alto, California 94304, USA.
Sarah R SmithScripps Institution of Oceanography, Integrative Oceanography Division, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, California 92093, USA.
Alexandra Z WordenCanadian Institute for Advanced Research, 180 Dundas Street W, Toronto, Ontario M5G 1Z8, Canada.
Gordon and Betty Moore Foundation · USMonterey Bay Aquarium Research Institute · USNational Center for Genome Resources · USUniversity of Southern California · USColumbia University · USDalhousie University · CAJ. Craig Venter Institute · USTriangle · USUniversity of California, Davis · USUniversity of California, San Diego · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protists, which are single-celled eukaryotes, critically influence the ecology and chemistry of marine ecosystems, but genome-based studies of these organisms have lagged behind those of other microorganisms. However, recent transcriptomic studies of cultured species, complemented by meta-omics analyses of natural communities, have increased the amount of genetic information available for poorly represented branches on the tree of eukaryotic life. This information is providing insights into the adaptations and interactions between protists and other microorganisms and macroorganisms, but many of the genes sequenced show no similarity to sequences currently available in public databases. A better understanding of these newly discovered genes will lead to a deeper appreciation of the functional diversity and metabolic processes in the ocean. In this Review, we summarize recent developments in our understanding of the ecology, physiology and evolution of protists, derived from transcriptomic studies of cultured strains and natural communities, and discuss how these novel large-scale genetic datasets will be used in the future.

Indexed as

Aquatic OrganismsBiological EvolutionEcosystemEnergy MetabolismEukaryotaTranscriptome

Identifiers

PMID27867198
OpenAlexW2554677631

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.