Evidence map›Paper›PMID 27867089›Full record

ReviewNeuroImage2018

Clinical vascular imaging in the brain at 7T.

Laurens Jl De Cocker, Arjen Lindenholz, Jaco Jm Zwanenburg, Anja G van der Kolk, Maarten Zwartbol, Peter R Luijten, Jeroen Hendrikse

Abstract readReview
In one paragraph

Review in NeuroImage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Observational
  6. Article
  7. High Resolution TOF-MRA Using Compressed Sensing-based Deep Learning Image Reconstruction for the Visualization of Lenticulostriate Arteries: A Preliminary Study.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. A radiomic model based on 7T intracranial vessel wall imaging for identification of culprit middle cerebral artery plaque associated with subcortical infarctions.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Time-of-flight MRA of intracranial vessels at 7 T.European radiology experimental · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laurens Jl De CockerDepartment of Radiology, University Medical Center Utrecht, The Netherlands; Department of Radiology, Kliniek Sint-Jan, Brussels, Belgium. Electronic address: laurens_de_cocker@hotmail.com.
Arjen LindenholzDepartment of Radiology, University Medical Center Utrecht, The Netherlands.
Jaco Jm ZwanenburgDepartment of Radiology, University Medical Center Utrecht, The Netherlands.
Anja G van der KolkDepartment of Radiology, University Medical Center Utrecht, The Netherlands.
Maarten ZwartbolDepartment of Radiology, University Medical Center Utrecht, The Netherlands.
Peter R LuijtenDepartment of Radiology, University Medical Center Utrecht, The Netherlands.
Jeroen HendrikseDepartment of Radiology, University Medical Center Utrecht, The Netherlands.

Funding

European Research Council 337333European Research Council 637024
6 · The paper itself

Abstract

Stroke and related cerebrovascular diseases are a major cause of mortality and disability. Even at standard-field-strengths (1.5T), MRI is by far the most sensitive imaging technique to detect acute brain infarctions and to characterize incidental cerebrovascular lesions, such as white matter hyperintensities, lacunes and microbleeds. Arterial time-of-flight (TOF) MR angiography (MRA) can depict luminal narrowing or occlusion of the major brain feeding arteries, and this without the need for contrast administration. Compared to 1.5T MRA, the use of high-field strength (3T) and even more so ultra-high-field strengths (7T), enables the visualization of the lumen of much smaller intracranial vessels, while adding a contrast agent to TOF MRA at 7T may enable the visualization of even more distal arteries in addition to veins and venules. Moreover, with 3T and 7T, the arterial vessel walls beyond the circle of Willis become visible with high-resolution vessel wall imaging. In addition, with 7T MRI, the brain parenchyma can now be visualized on a submillimeter scale. As a result, high-resolution imaging studies of the brain and its blood supply at 7T have generated new concepts of different cerebrovascular diseases. In the current article, we will discuss emerging clinical applications and future directions of vascular imaging in the brain at 7T MRI.

Indexed as

BrainCerebrovascular DisordersHumansMagnetic Resonance ImagingNeuroimaging

Identifiers

PMID27867089
PMCPMC5862656

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.