ArticleThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2017
Improved waitlist and transplant outcomes for pediatric lung transplantation after implementation of the lung allocation score.
Article in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Future prospects of pediatric lung transplantation.JHLT open · 2026Article
- Current opinion in pediatrics: pediatric lung transplantation in the 21 st century.Current opinion in pediatrics · 2026Review
- Pediatric Lung Transplantation Following Non-Transplant Cardiac Surgery: A Contemporary Analysis.Lung · 2026Article
- Waiting List Survival Trends in Pediatric Lung Transplantation: A National Cohort Study.Pediatric pulmonology · 2026Article
- Article
- Disparities in lung transplantation in children.Pediatric pulmonology · 2024Review
- Lobar graft evaluation in cadaveric lobar lung redo transplantation after living-donor lobar lung transplantation: a case report.Surgical case reports · 2024Article
- Lung transplantation in children.Turk gogus kalp damar cerrahisi dergisi · 2024Review
- Poor functional status at the time of waitlist for pediatric lung transplant is associated with worse pretransplant outcomes.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023Article
- Extracorporeal membrane oxygenation bridge to pediatric lung transplantation: Modern era analysis.Pediatric transplantation · 2023Article
- Bilateral lung transplantation for pediatric pulmonary arterial hypertension: perioperative management and one-year follow-up.Frontiers in cardiovascular medicine · 2023Article
- Seven-day in vivo testing of a novel, low-resistance, pumpless pediatric artificial lung for long-term support.Journal of pediatric surgery · 2022Article
- Bridging Children to Lung Transplantation Using Extracorporeal Membrane Oxygenation.Annals of the American Thoracic Society · 2022Article
- A pumpless artificial lung without systemic anticoagulation: The Nitric Oxide Surface Anticoagulation system.Journal of pediatric surgery · 2022Article
- Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2021Article
- Pediatric and neonatal extracorporeal life support: current state and continuing evolution.Pediatric surgery international · 2021Review
- Clinical outcomes and survival following lung transplantation in patients with pulmonary Langerhans cell histiocytosis.Respirology (Carlton, Vic.) · 2020Article
- Strategies for pediatric lung transplantation: bridging, listing and surgical technique.Annals of cardiothoracic surgery · 2020Article
- Improved survival in simultaneous lung-liver recipients and candidates in the modern era of lung allocation.The Journal of surgical research · 2018Article
- Impact on post-transplantation outcomes in pediatric patients undergoing heart-lung transplantation by recipient age at the time of transplantation.Annals of pediatric cardiologyArticle
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6 authors.
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Abstract
backgroundAlthough the lung allocation score (LAS) has not been considered valid for lung allocation to children, several additional policy changes for pediatric lung allocation have been adopted since its implementation. We compared changes in waitlist and transplant outcomes for pediatric and adult lung transplant candidates since LAS implementation.
methodsThe United Network for Organ Sharing database was reviewed for all lung transplant listings during the period 1995 to June 2014. Outcomes were analyzed based on date of listing (pre-LAS vs post-LAS) and candidate age at listing (adults >18 years, adolescents 12 to 17 years, children 0 to 11 years).
resultsOf the 39,962 total listings, 2,096 (5%) were for pediatric candidates. Median waiting time decreased after LAS implementation for all age groups (adults: 379 vs 83 days; adolescents: 414 vs 104 days; children: 211 vs 109 days; p < 0.001). The proportion of candidates reaching transplant increased after LAS (adults: 52.6% vs 71.6%, p < 0.001; adolescents: 40.3% vs 61.6%, p < 0.001; children: 42.4% vs 50.9%, p = 0.014), whereas deaths on the waitlist decreased (adults: 28.0% vs 14.4%, p < 0.001; adolescents: 33.1% vs 20.9%, p < 0.001; children: 32.2% vs 25.0%; p = 0.025), despite more critically ill candidates in all groups. Median recipient survival increased after LAS for adults and children (adults: 5.1 vs 5.5 years, p < 0.001; children: 6.5 vs 7.6 years, p = 0.047), but not for adolescents (3.6 vs 4.3 years, p = 0.295).
conclusionsImprovements in waiting time, mortality and post-transplant survival have occurred in children after LAS implementation. Continued refinement of urgency-based allocation to children and broader sharing of pediatric donor lungs may help to maximize these benefits.
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