Evidence map›Paper›PMID 27866341›Full record

ArticlePurinergic signalling2017

The role of the P2X7 receptor in murine cutaneous leishmaniasis: aspects of inflammation and parasite control.

Vanessa Ribeiro Figliuolo, Suzana Passos Chaves, Luiz Eduardo Baggio Savio, Maria Luiza Prates Thorstenberg, Érika Machado Salles, Christina Maeda Takiya, Maria Regina D'Império-Lima, Herbert Leonel de Matos Guedes, Bartira Rossi-Bergmann, Robson Coutinho-Silva

Open access · greenAbstract read
In one paragraph

Article in Purinergic signalling, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Altered purinergic P2X7 and ABiomedical journal · 2024
    Article
  5. Article
  6. Review
  7. Review
  8. P2RX7 at the Host-Pathogen Interface of Infectious Diseases.Microbiology and molecular biology reviews : MMBR · 2021
    Review
  9. Article
  10. P2YMediators of inflammation · 2020
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Purinergic Cooperation Between P2YFrontiers in immunology · 2018
    Article
  18. Review
  19. Purinergic Signalling: Therapeutic Developments.Frontiers in pharmacology · 2017
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Vanessa Ribeiro FigliuoloInstitute of Biophysics Carlos Chagas Filho, IBCCF/Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, 21941-902, Brazil.
Suzana Passos ChavesInstitute of Biophysics Carlos Chagas Filho, IBCCF/Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, 21941-902, Brazil.
Luiz Eduardo Baggio SavioInstitute of Biophysics Carlos Chagas Filho, IBCCF/Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, 21941-902, Brazil.
Maria Luiza Prates ThorstenbergInstitute of Biophysics Carlos Chagas Filho, IBCCF/Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, 21941-902, Brazil.
Érika Machado SallesImmunology Department, University of São Paulo - USP, São Paul, Brazil.
Christina Maeda TakiyaInstitute of Biophysics Carlos Chagas Filho, IBCCF/Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, 21941-902, Brazil.
Maria Regina D'Império-LimaImmunology Department, University of São Paulo - USP, São Paul, Brazil.
Herbert Leonel de Matos GuedesInstitute of Biophysics Carlos Chagas Filho, IBCCF/Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, 21941-902, Brazil.
Bartira Rossi-BergmannInstitute of Biophysics Carlos Chagas Filho, IBCCF/Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, 21941-902, Brazil.
Robson Coutinho-SilvaInstitute of Biophysics Carlos Chagas Filho, IBCCF/Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, 21941-902, Brazil. rcsilva@biof.ufrj.br.
National Institute of Amazonian Research · BRUniversidade Federal do Rio de Janeiro · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leishmania amazonensis is the etiological agent of diffuse cutaneous leishmaniasis. The immunopathology of leishmaniasis caused by L. amazonensis infection is dependent on the pathogenic role of effector CD4

Indexed as

AnimalsInflammationLeishmaniasis, Diffuse CutaneousMaleMiceMice, Inbred C57BLReceptors, Purinergic P2X7T-LymphocytesReceptors, Purinergic P2X7ATPL. amazonensisMacrophagesP2X7T cells

Identifiers

PMID27866341
PMCPMC5432475
OpenAlexW2554557164

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.