Evidence map›Paper›PMID 27866319›Full record

ArticleMycopathologia2017

Successful Posaconazole Therapy of Disseminated Alternariosis due to Alternaria infectoria in a Heart Transplant Recipient.

Pavlina Lyskova, Milos Kubanek, Vit Hubka, Eva Sticova, Ludek Voska, Dana Kautznerova, Miroslav Kolarik, Petr Hamal, Martina Vasakova

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Cutaneous Alternariosis Caused byJournal of fungi (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Diffuse primary cutaneous infection byMedical mycology case reports · 2020
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Pavlina LyskovaLaboratory of Medical Mycology, Department of Parasitology, Mycology and Mycobacteriology Prague, Public Health Institute in Usti nad Labem, Sokolovska 60, 186 00, Prague 8, Czech Republic. pavlina.lyskova@zuusti.cz.ORCID http://orcid.org/0000-0002-3131-5924
Milos KubanekDepartment of Cardiology, Institute for Clinical and Experimental Medicine, Videnska 1958, 140 21, Prague 4, Czech Republic.
Vit HubkaDepartment of Botany, Faculty of Science, Charles University in Prague, Benatska 2, 128 01, Prague 2, Czech Republic.
Eva SticovaDepartment of Pathology, Institute for Clinical and Experimental Medicine, Videnska 1958, 140 21, Prague 4, Czech Republic.
Ludek VoskaDepartment of Pathology, Institute for Clinical and Experimental Medicine, Videnska 1958, 140 21, Prague 4, Czech Republic.
Dana KautznerovaDepartment of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Videnska 1958, 140 21, Prague 4, Czech Republic.
Miroslav KolarikDepartment of Botany, Faculty of Science, Charles University in Prague, Benatska 2, 128 01, Prague 2, Czech Republic.
Petr HamalDepartment of Microbiology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Hnevotinska 3, 775 15, Olomouc, Czech Republic.
Martina VasakovaDepartment of Respiratory Medicine, Thomayer Hospital, 1st Medical School and Charles University, Prague Videnska 800, 140 59, Prague 4, Czech Republic.
Institute of Clinical and Experimental Medicine · CZCharles University · CZMycologie et Sécurité des Aliments · FRPalacký University Olomouc · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of phaeohyphomycosis caused by Alternaria infectoria in a 61-year-old heart transplant recipient with multiple skin lesions and pulmonary infiltrates. The infection spread via the haematogenous route from the primary cutaneous lesions into the lungs. The diagnosis was based on the histopathological examination, direct microscopy, skin lesion cultures and detection of Alternaria DNA in the bronchoalveolar lavage fluid using molecular methods. The treatment consisted of a combination of surgical excision and systemic antifungal therapy. Voriconazole was the first agent used but had a weak effect. Posaconazole was subsequently used to achieve a successful response. The isolate was identified as A. infectoria by sequencing of the rDNA ITS region and the partial β-tubulin gene.

Indexed as

AlternariaAntifungal AgentsDebridementDermatomycosesDNA, FungalDNA, Ribosomal SpacerHeart TransplantationHistocytochemistryHumansLung Diseases, FungalMaleMicroscopyMiddle AgedPhaeohyphomycosisSequence Analysis, DNATransplant RecipientsAntifungal AgentsDNA, FungalDNA, Ribosomal SpacerposaconazoleTriazolesTubulinAlternariosisHeart transplantationPhaeohyphomycosisPulmonary infection

Identifiers

PMID27866319
OpenAlexW2550140799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.