ReviewJournal of molecular evolution2016
The RNA World at Thirty: A Look Back with its Author.
Review in Journal of molecular evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- The Emergence of Life in the Light of Evolution.ArXiv · 2026Article
- Cancer cell target discovery: comparing laboratory evolution of expanded DNA six-nucleotide alphabets with standard four-nucleotide alphabets.Nucleic acids research · 2025Article
- A Short Tale of the Origin of Proteins and Ribosome Evolution.Microorganisms · 2022Review
- Biology of aging: Oxidative stress and RNA oxidation.Molecular biology reports · 2022Review
- Viruses in astrobiology.Frontiers in microbiology · 2022Review
- Oxidative RNA Damage in the Pathogenesis and Treatment of Type 2 Diabetes.Frontiers in physiology · 2022Review
- Review
- Reductive Charge Transfer through an RNA Aptamer.Angewandte Chemie (International ed. in English) · 2020Article
- Recent Advances: Molecular Mechanism of RNA Oxidation and Its Role in Various Diseases.Frontiers in molecular biosciences · 2020Review
- Sulfurization of H-Phosphonate Diesters by Elemental Sulfur under Aqueous Conditions.ACS omega · 2017Article
- Cryosphere and Psychrophiles: Insights into a Cold Origin of Life?Life (Basel, Switzerland) · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thirty years ago, molecular biologist Walter Gilbert published his RNA world hypothesis, which posited that early in evolution living systems were composed entirely of RNA. Proposed in the immediate wake of the discovery that certain RNA molecules were capable of catalyzing biological reactions, the hypothesis ascribed both of life's essential functions, namely carrying information and catalysis-respectively, performed by DNA and proteins in most modern life systems-to RNA, which were labeled as ribozymes. In the years since its inception, the RNA world has been greeted with equal parts enthusiasm and opposition from the origins of life research community, of which Gilbert neither was, nor really became, a part. For this special historical issue of the Journal of Molecular Evolution, Gilbert agreed to revisit his hypothesis and share his memories about the theory's origins and his insights into its fate in the years since he first published his idea.
Indexed as
Identifiers
27866234What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.