ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2017
Impact of body mass index on risk of acute kidney injury and mortality in elderly patients undergoing hip fracture surgery.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.
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30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- The incidence and influencing factors of postoperative acute kidney injury in elderly patients with hip fractures: A meta-analyses.PloS one · 2025Pooled it
- Does vitamin D deficiency affect functional outcomes in hip fracture patients? A meta-analysis of cohort studies.Journal of endocrinological investigation · 2024Pooled it
- Nutrition support for acute kidney injury 2020-consensus of the Taiwan AKI task force.Journal of the Chinese Medical Association : JCMA · 2022Pooled it
- The prevalence and risk factors of acute kidney injury in patients undergoing hip fracture surgery: a meta-analysis.Bioengineered · 2021Pooled it
- Prevalence and risk factors of acute kidney injury in patients with hip fractures.Journal of perioperative practice · 2026Observational
- Obesity and mortality in KDIGO stage 3 acute kidney injury: a machine learning-driven retrospective cohort study.BMC nephrology · 2025Article
- Association of Geriatric Nutritional Risk Index with short-term mortality in patients with severe acute kidney injury: a retrospective cohort study.Renal failure · 2024Observational
- Outcome and Determining Characteristics of ICU Patients with Acute Kidney Injury in a Low-Income Country, a Multicenter Experience.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024Article
- Incidence and predictors of acute kidney injury after elective surgery for lumbar degenerative disease: A 13-year analysis of the US Nationwide Inpatient Sample.Journal of the Chinese Medical Association : JCMA · 2024Article
- Early Sepsis-Associated Acute Kidney Injury and Obesity.JAMA network open · 2024Article
- Article
- Obese elderly patients with hip fractures may have better survival outcomes after surgery.Archives of orthopaedic and trauma surgery · 2023Article
- Construction and Validation of a Nomogram for Predicting Acute Kidney Injury After Hip Fracture Surgery.Clinical interventions in aging · 2023Article
- Acute kidney injury after major orthopedic surgery: A retrospective study of frequency and related risk factors.Acta orthopaedica et traumatologica turcica · 2022Article
- Incidence and risk factors of acute kidney injury after femoral neck fracture in elderly patients: a retrospective case-control study.BMC musculoskeletal disorders · 2022Article
- A Machine Learning-Based Prediction Model for Acute Kidney Injury in Patients With Congestive Heart Failure.Frontiers in cardiovascular medicine · 2022Article
- The effect of body mass index on the development of acute kidney injury and mortality in intensive care unit: is obesity paradox valid?Renal failure · 2021Article
- The Association Between BMI and Mortality in Surgical Patients.World journal of surgery · 2021Article
- Vitamin D deficiency is associated with reduced mobility after hip fracture surgery: a prospective study.The American journal of clinical nutrition · 2020Article
- Use of sodium-glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020Article
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5 authors at 1 institution in 1 country.
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Abstract
The literature is limited regarding risk factors for acute kidney injury (AKI) and mortality in hip fracture patients, although AKI is common in these patients. While obese patients were at increased risk of AKI, underweight patients with and without AKI had elevated mortality for up to 1 year after hip fracture surgery, compared with normal-weight patients.
introductionThis study aimed to examine risk of postoperative AKI and subsequent mortality, by body mass index (BMI) level, in hip fracture surgery patients aged 65 and over.
methodsA regional cohort study using medical databases was used. We included all patients who underwent surgery to repair a hip fracture during the years 2005-2011 (n = 13,529) at hospitals in Northern Denmark. We calculated cumulative risk of AKI by BMI level during 5 days postsurgery and subsequent short-term (6-30 days postsurgery) and long-term (31-365 days post-surgery) mortality. We calculated crude and adjusted hazard ratios (aHRs) for AKI and death with 95% confidence intervals (CIs), comparing underweight, overweight, and obese patients with normal-weight patients.
resultsRisks of AKI within five postoperative days were 11.9, 10.1, 12.5, and 17.9% for normal-weight, underweight, overweight, and obese patients, respectively. Among those who developed AKI, short-term mortality was 14.1% for normal-weight patients compared to 23.1% for underweight (aHR 1.7 (95% CI 1.2-2.4)), 10.7% for overweight (aHR 0.9 (95% CI 0.6-1.1)), and 15.2% for obese (aHR 0.9 (95% CI 0.6-1.4)) patients. Long-term mortality was 24.5% for normal-weight, 43.8% for underweight (aHR 1.6 (95% CI 1.0-2.6)), 20.5% for overweight (aHR 0.8 (95% CI 0.6-1.2)), and 21.4% for obese (aHR 1.1 (95% CI 0.7-1.8) AKI patients. Similar associations between BMI and mortality were observed among patients without postoperative AKI, although the absolute mortality risk estimates by BMI were considerably lower in patients without than in those with AKI.
conclusionsObese patients were at increased risk of AKI compared with normal-weight patients. Among patients with and without postoperative AKI, overweight and obesity were not associated with mortality. Compared to normal-weight patients, underweight patients had elevated mortality for up to 1 year after hip fracture surgery irrespective of the presence of AKI. The absolute mortality risks were higher in all BMI groups with the presence of AKI.
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