ArticleJournal of the American Heart Association2016
Relationship Between Anemia and Mortality Outcomes in a National Acute Coronary Syndrome Cohort: Insights From the UK Myocardial Ischemia National Audit Project Registry.
Article in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
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Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.
- Liberal versus restrictive red blood cell transfusion strategy in acute coronary syndrome and anemia: an updated systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Individualized transfusion decisions to minimize adverse cardiovascular outcomes in patients with acute myocardial infarction and anemia.American heart journal · 2025Trial
- Anemia Acuity Effect on Transfusion Strategies in Acute Myocardial Infarction: A Secondary Analysis of the MINT Trial.JAMA network open · 2024Trial
- Association between anemia and mortality in patients with acute coronary syndrome treated with percutaneous coronary intervention and contemporary lipid-lowering therapy.Heart and vessels · 2021Trial
- Erythrocyte and Platelet Indices at Admission and Discharge Stratify Long-Term Cardiovascular Risk After Invasive Treatment of Myocardial Infarction.Journal of clinical medicine · 2026Article
- Association Between Anemia and Prognosis in Patients With Acute Coronary Syndrome and Atrial Fibrillation.Angiology · 2026Article
- Elevated Red Blood Cell Distribution Width Predicts Mortality and Major Adverse Cardiovascular Events After Acute Myocardial Infarction: A Large Propensity Score-Matched Cohort Study.Journal of clinical medicine · 2026Article
- Development of a risk factor nomogram prediction model for patients with acute coronary syndrome complicated by hypertension using LASSO regression analysis.BMC cardiovascular disorders · 2025Article
- Quality of care and long-term survival after ST-elevation myocardial infarction in adults with cancer.European heart journal. Quality of care & clinical outcomes · 2025Article
- The Negative Influence and Adverse Outcome of Red Blood Cell Transfusion in Contemporary Percutaneous Coronary Interventions.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025Review
- Usefulness of the AHEAD score for prediction of all-cause death in patients with acute and chronic coronary syndromes.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Anemia as a potent marker of in-hospital mortality in patients admitted to the cardiac intensive care unit: Data from the Critical Care Cardiology Trials Network (CCCTN) Registry.Journal of intensive medicine · 2025Article
- Impact of Hemoglobin and Iron Deficiency on Mortality in Patients with Acute Myocardial Infarction in Intensive Care Units: A Retrospective Study from MIMIC-IV.Reviews in cardiovascular medicine · 2025Article
- Hemoglobin-to-Creatinine Ratio Predicts One-Year Adverse Clinical Outcomes in ST-Elevation Myocardial Infarction: Retrospective and Propensity Score Matched Analysis.Journal of clinical medicine · 2025Article
- Impact of Socioeconomic Disparities on Care and Outcomes of Cancer Patients Presenting With STEMI Between 2005 and 2019; a Nationwide British Study.Clinical cardiology · 2025Article
- RURUS SURYAWAN Score: A Novel Scoring System to Predict 30-Day Mortality for Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.Journal of clinical medicine · 2025Article
- Predicting Mortality in Patients Hospitalized With Acute Myocardial Infarction: From the National Cardiovascular Data Registry.Circulation. Cardiovascular quality and outcomes · 2025Article
- Ischaemic and bleeding risk after ST-elevation myocardial infarction in patients with active cancer: a nationwide study.European heart journal open · 2025Article
- Article
- Bleeding risk prediction after acute myocardial infarction-integrating cancer data: the updated PRECISE-DAPT cancer score.European heart journal · 2024Article
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8 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundWe aim to determine the prevalence of anemia in acute coronary syndrome (ACS) patients and compare their clinical characteristics, management, and clinical outcomes to those without anemia in an unselected national ACS cohort. METHODS AND
resultsThe Myocardial Ischemia National Audit Project (MINAP) registry collects data on all adults admitted to hospital trusts in England and Wales with diagnosis of an ACS. We conducted a retrospective cohort study by analyzing patients in this registry between January 2006 and December 2010 and followed them up until August 2011. Multiple logistic regressions were used to determine factors associated with anemia and the adjusted odds of 30-day mortality with 1 g/dL incremental hemoglobin increase and the 30-day and 1-year mortality for anemic compared to nonanemic groups. Analyses were adjusted for covariates. Our analysis of 422 855 patients with ACS showed that 27.7% of patients presenting with ACS are anemic and that these patients are older, have a greater prevalence of renal disease, peripheral vascular disease, diabetes mellitus, and previous acute myocardial infarction, and are less likely to receive evidence-based therapies shown to improve clinical outcomes. Finally, our analysis suggests that anemia is independently associated with 30-day (OR 1.28, 95% CI 1.22-1.35) and 1-year mortality (OR 1.31, 95% CI 1.27-1.35), and we observed a reverse J-shaped relationship between hemoglobin levels and mortality outcomes.
conclusionsThe prevalence of anemia in a contemporary national ACS cohort is clinically significant. Patients with anemia are older and multimorbid and less likely to receive evidence-based therapies shown to improve clinical outcomes, with the presence of anemia independently associated with mortality outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.