Evidence map›Paper›PMID 27866066›Full record

ArticleCancer epidemiology2017

Terminate lung cancer (TLC) study-A mixed-methods population approach to increase lung cancer screening awareness and low-dose computed tomography in Eastern Kentucky.

Roberto Cardarelli, David Reese, Karen L Roper, Kathryn Cardarelli, Frances J Feltner, Jamie L Studts, Jennifer R Knight, Debra Armstrong, Anthony Weaver, Dana Shaffer

Abstract read
In one paragraph

Article in Cancer epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Knowledge translation strategies to enhance lung cancer screening programme implementation: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Assessing the Effectiveness of Cancer Screening Interventions Targeting Appalachian Populations: A Systematic Review.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2021
    Pooled it
  3. Pooled it
  4. Trial
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  11. Cancer disparities in Appalachian Kentucky.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Improving Lung Cancer Screening Access for Individuals With Serious Mental Illness.Journal of the American College of Radiology : JACR · 2019
    Article
  19. Rural-Urban Differences in Cancer Incidence and Trends in the United States.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018
    Article
  20. An Overview of the National Cancer Institute's Initiatives to Accelerate Rural Cancer Control Research.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Roberto CardarelliUniversity of Kentucky College of Medicine, Department of Family & Community Medicine/Division of Community Medicine, 2195 Harrodsburg Road, Lexington, KY, 40504-3504 USA.
David ReeseAppalachian Osteopathic Postgraduate Training Institute Consortium, Pikeville, KY, USA.
Karen L RoperUniversity of Kentucky College of Medicine, Department of Family & Community Medicine/Division of Community Medicine, 2195 Harrodsburg Road, Lexington, KY, 40504-3504 USA. Electronic address: karen.roper@uky.edu.
Kathryn CardarelliUniversity of Kentucky College of Public Health/Department of Health, Behavior, & Society, Lexington, KY, USA.
Frances J FeltnerUniversity of Kentucky College of Medicine, Center of Excellence in Rural Health & Kentucky Homeplace, Hazard, KY, USA.
Jamie L StudtsUniversity of Kentucky College of Medicine, Department of Behavioral Science, Lexington, KY, USA.
Jennifer R KnightUniversity of Kentucky College of Public Health/Department of Health Management and Policy, Lexington, KY, USA.
Debra ArmstrongThe Kentucky Cancer Program, Lexington, KY, USA.
Anthony WeaverUniversity of Kentucky College of Medicine, Morehead Campus Department of Internal Medicine, Morehead, KY, USA.
Dana ShafferUniversity of Pikeville, Kentucky College of Osteopathic Medicine, Appalachian Osteopathic Postgraduate Training Consortium, Pikeville, KY, USA.

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI KATHLEEN L. O'CONNOR · 2013 to 2026
$38.3M
Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
Kentucky Center for Clinical and Translational ScienceUL1TR000117 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$13.3M
NCATS NIH HHS UL1 TR000117NCATS NIH HHS UL1 TR001998NCI NIH HHS P30 CA177558
6 · The paper itself

Abstract

For low dose CT lung cancer screening to be effective in curbing disease mortality, efforts are needed to overcome barriers to awareness and facilitate uptake of the current evidence-based screening guidelines. A sequential mixed-methods approach was employed to design a screening campaign utilizing messages developed from community focus groups, followed by implementation of the outreach campaign intervention in two high-risk Kentucky regions. This study reports on rates of awareness and screening in intervention regions, as compared to a control region.

Indexed as

Early Detection of CancerFemaleHumansKentuckyLung NeoplasmsMaleMass ScreeningMiddle AgedRiskTomography, X-Ray ComputedAppalachiaLung cancerPreventionScreening

Identifiers

PMID27866066
PMCPMC5369643

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.