Evidence map›Paper›PMID 27865183›Full record

ArticleInternational journal of cardiology2017

Feasibility of low radiation dose retrospectively-gated cardiac CT for functional analysis in adult congenital heart disease.

Daniel W Groves, Laura J Olivieri, Sujata M Shanbhag, Kathie C Bronson, Jeannie H Yu, Evan A Nelson, Shirley F Rollison, Michael S Stagliano, Anitha S John, Karen Kuehl and 1 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Daniel W GrovesDepartment of Health and Human Services, Advanced Cardiovascular Imaging Laboratory, Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Laura J OlivieriDepartment of Cardiology, Children's National Medical Center, Washington, DC, USA.
Sujata M ShanbhagDepartment of Health and Human Services, Advanced Cardiovascular Imaging Laboratory, Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Kathie C BronsonDepartment of Health and Human Services, Advanced Cardiovascular Imaging Laboratory, Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Jeannie H YuDepartment of Health and Human Services, Advanced Cardiovascular Imaging Laboratory, Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Evan A NelsonDepartment of Health and Human Services, Advanced Cardiovascular Imaging Laboratory, Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Shirley F RollisonDepartment of Health and Human Services, Advanced Cardiovascular Imaging Laboratory, Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Michael S StaglianoDepartment of Health and Human Services, Advanced Cardiovascular Imaging Laboratory, Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Anitha S JohnDepartment of Cardiology, Children's National Medical Center, Washington, DC, USA.
Karen KuehlDepartment of Cardiology, Children's National Medical Center, Washington, DC, USA.
Marcus Y ChenDepartment of Health and Human Services, Advanced Cardiovascular Imaging Laboratory, Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: chenmy@nhlbi.nih.gov.
National Institutes of Health · USChildren's National · US

Funding

Cardiovascular CT Clinical ResearchZIAHL006220 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CHEN, MARCUS · 2017 to 2025
$22.5M
Cardiovascular CT ResearchZIAHL006138 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI ARAI, ANDREW · 2011 to 2016
$7.3M
Intramural NIH HHS Z99 HL999999Intramural NIH HHS ZIA HL006138Intramural NIH HHS ZIA HL006220
6 · The paper itself

Abstract

backgroundThe use of cardiac computed tomography (CT) in the evaluation of adult congenital heart disease patients is limited due to concerns of high radiation doses. The purpose of this study was to prospectively assess whether low radiation dose cardiac CT is feasible to evaluate ventricular systolic function in adults with congenital heart disease.

methodsThe study group included 30 consecutive patients with significant congenital heart disease who underwent a total of 35 ECG-gated cardiac CT scans utilizing a 320-detector row CT scanner. Each study included a non-contrast scan and subsequent contrast-enhanced retrospectively-gated acquisition. Effective radiation dose was estimated by multiplying the dose length product by a k-factor of 0.014mSv/mGycm.

resultsThe mean age of the patients was 34.4±8.9years, 60% were men, and mean body mass index was 24.2±4.3kg/m

conclusionsA low radiation contrast-enhanced, retrospectively-gated cardiac CT with a median radiation dose of less than 1mSv was successful in evaluating ventricular systolic function in 30 consecutive adult congenital heart disease patients who underwent a total of 35 scans.

Indexed as

Cardiac-Gated Imaging TechniquesTomography, X-Ray ComputedAdultContrast MediaFeasibility StudiesFemaleHeart Defects, CongenitalHumansMaleMiddle AgedProspective StudiesRadiation DosageYoung AdultContrast MediaAdult congenital heart diseaseCardiac computed tomographyRadiation doseSystolic function

Identifiers

PMID27865183
PMCPMC6323633
OpenAlexW2550922082

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.