Evidence map›Paper›PMID 27864853›Full record

ArticleSynapse (New York, N.Y.)2017

PET radiotracer development for imaging high-affinity state of dopamine D2 and D3 receptors: Binding studies of fluorine-18 labeled aminotetralins in rodents.

Jogeshwar Mukherjee, Divya Majji, Jasmeet Kaur, Cristian C Constantinescu, Tanjore K Narayanan, Bingzhi Shi, Mohamed T Nour, Min-Liang Pan

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synapse (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03714763 naunknown statusnot on this mapstarted 2018, after this paper: background citation

The Predictive Value of Positron Emission Tomography-Magnetic Resonance (PET-MR) Mediated Dopamine D2 Receptors Imaging in the Drug Therapy of Nonfunctioning Pituitary Adenoma

TypeinterventionalSponsorZhebao WuRan2018 to 2022Enrolled50ConditionsPituitary AdenomaArmsDrug treatment, Surgery
NCT03717454 naunknown statusnot on this mapstarted 2018, after this paper: background citation

The Predictive Value of Positron Emission Tomography-Magnetic Resonance (PET-MR) Mediated Dopamine D2 Receptors Imaging in the Drug Therapy of of Prolactinomas.

TypeinterventionalSponsorZhebao WuRan2018 to 2022Enrolled50ConditionsProlactinomaArmsSurgery, Drug treatment
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Characterization of [ACS omega · 2026
    Article
  2. Review
  3. [Frontiers in neuroscience · 2021
    Article
  4. Review
  5. New Dopamine D2 Receptor Agonist, [ACS chemical neuroscience · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jogeshwar MukherjeeDepartment of Radiological Sciences, Preclinical Imaging Center, University of California-Irvine, Irvine, California, 92697, USA.
Divya MajjiDepartment of Radiological Sciences, Preclinical Imaging Center, University of California-Irvine, Irvine, California, 92697, USA.
Jasmeet KaurDepartment of Radiological Sciences, Preclinical Imaging Center, University of California-Irvine, Irvine, California, 92697, USA.
Cristian C ConstantinescuDepartment of Radiological Sciences, Preclinical Imaging Center, University of California-Irvine, Irvine, California, 92697, USA.
Tanjore K NarayananDepartment of Nuclear Medicine, Kettering Medical Center, Dayton, Ohio, 45429, USA.
Bingzhi ShiDepartment of Nuclear Medicine, Kettering Medical Center, Dayton, Ohio, 45429, USA.
Mohamed T NourDepartment of Radiological Sciences, Preclinical Imaging Center, University of California-Irvine, Irvine, California, 92697, USA.
Min-Liang PanDepartment of Radiological Sciences, Preclinical Imaging Center, University of California-Irvine, Irvine, California, 92697, USA.

Funding

Vancouver Drug Users Study: The Impacts of Evolving Drug Use Patterns on HIV/AIDSU01DA038886 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI DEBECK, KORA, HAYASHI, KANNA · 2015 to 2024
$12.1M
Dopamine D2/D3 Receptor Agonists for PET ImagingR01EB006110 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI MUKHERJEE, JOGESHWAR · 2007 to 2010
$1.4M
Fluorine-18 Labeled Functional Dopamine Receptor Imaging AgentsR21DA038866 · NIDA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MUKHERJEE, JOGESHWAR · 2015 to 2017
$693k
NIBIB NIH HHS R01 EB006110NIDA NIH HHS R21 DA038866NIDA NIH HHS U01 DA038886
6 · The paper itself

Abstract

Imaging the high-affinity, functional state (HA) of dopamine D2 and D3 receptors has been pursued in PET imaging studies of various brain functions. We report further evaluation of

Indexed as

AnimalsBrainFluorine RadioisotopesMalePositron-Emission TomographyRadiopharmaceuticalsRatsRats, Sprague-DawleyReceptors, Dopamine D2Receptors, Dopamine D3TetrahydronaphthalenesFluorine RadioisotopesRadiopharmaceuticalsReceptors, Dopamine D2Receptors, Dopamine D3Tetrahydronaphthalenesautoradiographydopamine receptorfluorinated agonistshigh-affinity statePET

Identifiers

PMID27864853
PMCPMC5363407

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.