Evidence map›Paper›PMID 27864827›Full record

ReviewBritish journal of pharmacology2017

Biomarkers of oxidative and nitro-oxidative stress: conventional and novel approaches.

Ana Cipak Gasparovic, Neven Zarkovic, Kamelija Zarkovic, Khrystyna Semen, Danylo Kaminskyy, Olha Yelisyeyeva, Serge P Bottari

Abstract readReview
In one paragraph

Review in British journal of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Trial
  2. Phase II Study of Iniparib with Concurrent Chemoradiation in Patients with Newly Diagnosed Glioblastoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana Cipak GasparovicLabOS, Rudjer Boskovic Institute, Zagreb, Croatia.
Neven ZarkovicLabOS, Rudjer Boskovic Institute, Zagreb, Croatia.
Kamelija ZarkovicDivision of Pathology, Clinical Hospital Centre, University of Zagreb School of Medicine, Zagreb, Croatia.
Khrystyna SemenDepartment of Propedeutics of Internal Medicine #2, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.
Danylo KaminskyyDepartment of Pharmaceutical, Organic, and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.
Olha YelisyeyevaDepartment of Histology, Cytology and Embryology, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.
Serge P BottariInstitute for Advanced Biosciences, INSERM U1029, CNRS UMR 5309, Grenoble-Alps University Medical School, Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The concept of oxidative stress (OS) that connects altered redox biology with various diseases was introduced 30 years ago and has generated intensive research over the past two decades. Whereas it is now commonly accepted that macromolecule oxidation in response to ROS is associated with a variety of pathologies, the emergence of NO as a key regulator of redox signalling has led to the discovery of the pathophysiological significance of reactive nitrogen species (RNS). RNS can elicit various modifications of macromolecules and lead to nitrative or nitro-OS. In order to investigate oxidative and nitro-OS in human and in live animal models, circulating biomarker assays have been developed. This article provides an overview of key biomarkers used to assess lipid peroxidation and NO/NO LINKED ARTICLES: This article is part of a themed section on Redox Biology and Oxidative Stress in Health and Disease. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v174.12/issuetoc.

Indexed as

AnimalsBiomarkersHumansNitric OxideOxidation-ReductionOxidative StressReactive Nitrogen SpeciesBiomarkersNitric OxideReactive Nitrogen Species

Identifiers

PMID27864827
PMCPMC5446576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.