ArticleSurgical endoscopy2017
Pre-treatment Eckardt score is a simple factor for predicting one-year peroral endoscopic myotomy failure in patients with achalasia.
Article in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Peroral endoscopic myotomy in children with achalasia: A review of the literature.World journal of gastrointestinal endoscopy · 2025Review
- Effect of sex on the outcomes of peroral endoscopic myotomy for the treatment of achalasia.World journal of gastroenterology · 2025Article
- An "esophageal rosette" sign is useful for predicting favorable outcomes in peroral endoscopic myotomy for esophageal achalasia.Esophagus : official journal of the Japan Esophageal Society · 2025Article
- Gastroesophageal reflux disease over time in endoscopic versus surgical myotomy for treatment of achalasia: Systematic review and meta-analysis.Endoscopy international open · 2025Review
- Lung cancer metastasis-induced distal esophageal segmental spasm confirmed by individualized peroral endoscopic myotomy: A case report.World journal of gastrointestinal surgery · 2024Article
- Automatic three-dimensional reconstruction of the oesophagus in achalasia patients undergoing POEM: an innovative approach for evaluating treatment outcomes.BMJ open gastroenterology · 2024Article
- Long-term efficacy of peroral endoscopic myotomy for achalasia under different criteria.Surgical endoscopy · 2024Article
- Peroral Endoscopic Myotomy for Achalasia in Older Adults: A Retrospective Analysis of 39 Cases with a Minimum Follow-Up of 5 Years.Dysphagia · 2023Article
- Do preoperative endoscopic interventions predict symptom recurrence or reintervention after peroral endoscopic myotomy?Surgical endoscopy · 2023Article
- Pathogenesis, clinical manifestations, diagnosis, and treatment progress of achalasia of cardia.World journal of clinical cases · 2023Review
- Correlation between our symptom-based scoring system and the Eckardt score for assessing patients with esophageal achalasia.Surgery today · 2022Article
- Review
- Risk factors for clinical failure of peroral endoscopic myotomy in achalasia.Frontiers in medicine · 2022Review
- Beyond the Eckardt Score: Patient-Reported Outcomes Measures in Esophageal Disorders.Current gastroenterology reports · 2021Review
- Per-oral endoscopic dual myotomy for the treatment of achalasia.Esophagus : official journal of the Japan Esophageal Society · 2021Article
- Long-term clinical results of per-oral endoscopic myotomy (POEM) for achalasia: First report of more than 10-year patient experience as assessed with a questionnaire-based survey.Endoscopy international open · 2021Article
- Treatment challenges of sigmoid-shaped esophagus and severe achalasia.Annals of medicine and surgery (2012) · 2021Review
- Effect of peroral endoscopic myotomy in geriatric patients: a propensity score matching study.Surgical endoscopy · 2020Article
- 2019 Seoul Consensus on Esophageal Achalasia Guidelines.Journal of neurogastroenterology and motility · 2020Review
- Short-term safety and efficacy of peroral endoscopic myotomy for the treatment of achalasia in children.Journal of gastroenterology · 2020Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeroral endoscopic myotomy (POEM) is a novel treatment for achalasia with excellent outcomes. But the predictor for treatment failure is not well defined. This study was aimed to prospectively investigate the factors for predicting failed POEM.
methodsFrom June 2011 to May 2015, a total of 115 achalasia patients treated by POEM were included for the retrospective cohort study from Nanfang Hospital and the First People's Hospital of Yunnan Province. Patients were followed up with Eckardt score, high-resolution manometry and endoscope. POEM failure was defined as primary failure (Eckardt score failed to decrease to 3 or below) and recurrences (decrease of Eckardt score to 3 or below, then rise to more than 3) during one-year follow-up. Univariate and multivariate Cox regression analyses were performed to assess the predictive factor. For the associated factor, receiver operating characteristic curve (ROC) was utilized to determine the cutoff value of the predicting factor.
resultsThe failure rate of POEM after 1 year was 7.0% (8/115), including 5 primary failure cases and 3 recurrences. Multivariate analysis showed higher pre-treatment Eckardt score was the single independent factor associated with POEM failure [9.5 (6-12) vs. 7 (2-12), odds ratio (OR) 2.24, 95 confidence interval (95% CI) 1.39-3.93, p = 0.001]. The cutoff value (Eckardt score ≥9) had 87.5 sensitivity (95% CI 47.3-99.7%) and 73.8% specificity (95% CI 64.4-81.9%) for predicting failed POEM.
conclusionsPre-treatment Eckardt score could be a predictive factor for failed POEM. Eckardt score ≥9 was associated with high sensitivity and specificity for predicting POEM failure.
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