Evidence map›Paper›PMID 27864638›Full record

Trial reportEuropean journal of applied physiology2017

Effects of caffeine on neuromuscular fatigue and performance during high-intensity cycling exercise in moderate hypoxia.

Bruno P C Smirmaul, Antonio Carlos de Moraes, Luca Angius, Samuele M Marcora

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of applied physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 8 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 8 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Bruno P C SmirmaulDepartment of Physical Education, São Paulo State University (UNESP), Rio Claro, SP, Brazil.
Antonio Carlos de MoraesFaculty of Physical Education, University of Campinas (UNICAMP), São Paulo, SP, Brazil.
Luca AngiusEndurance Research Group, School of Sport and Exercise Sciences, University of Kent at Medway, Chatham Maritime, Kent, ME4 4AG, UK.
Samuele M MarcoraEndurance Research Group, School of Sport and Exercise Sciences, University of Kent at Medway, Chatham Maritime, Kent, ME4 4AG, UK. s.m.marcora@kent.ac.uk.
University of Kent · GBUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the effects of caffeine on performance, neuromuscular fatigue and perception of effort during high-intensity cycling exercise in moderate hypoxia.

methodsSeven adult male participants firstly underwent an incremental exercise test on a cycle ergometer in conditions of acute normobaric hypoxia (fraction inspired oxygen = 0.15) to establish peak power output (PPO). In the following two visits, they performed a time to exhaustion test (78 ± 3% PPO) in the same hypoxic conditions after caffeine ingestion (4 mg kg

resultsCaffeine significantly improved time to exhaustion by 12%. A significant decrease in subjective fatigue was found after caffeine consumption. Perception of effort and surface electromyographic signal amplitude of the vastus lateralis were lower and heart rate was higher in the caffeine condition when compared to placebo. However, caffeine did not reduce the peripheral and central fatigue induced by high-intensity cycling exercise in moderate hypoxia.

conclusionThe caffeine-induced improvement in time to exhaustion during high-intensity cycling exercise in moderate hypoxia seems to be mediated by a reduction in perception of effort, which occurs despite no reduction in neuromuscular fatigue.

Indexed as

Athletic PerformanceExerciseAdultCaffeineCentral Nervous System StimulantsHumansHypoxiaMaleMuscle FatigueMuscle, SkeletalCaffeineCentral Nervous System StimulantsAltitudeCentral fatigueExercise performancePerception of effortPeripheral fatigue

Identifiers

PMID27864638
PMCPMC5306327
OpenAlexW2552993682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.