Evidence map›Paper›PMID 27864616›Full record

Trial reportWorld journal of surgery2017

Randomized Clinical Trial Comparing Cyanoacrylate Glue Versus Suture Fixation in Lichtenstein Hernia Repair: 7-Year Outcome Analysis.

M Matikainen, J Kössi, S Silvasti, T Hulmi, H Paajanen

Registry-linked trialAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00659542 (Randomized Study of Mesh Fixation With Absorbable Sutures or Glubran Tissue Sealant in Lichtenstein Hernioplasty), which is not on this map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00659542 phase2completednot on this map

Randomized Study of Mesh Fixation With Absorbable Sutures or Glubran Tissue Sealant in Lichtenstein Hernioplasty

TypeinterventionalSponsorKuopio University HospitalRan2007 to 2009Enrolled300ConditionsInguinal HerniaArmscyanoacrylate glue
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Long term inguinal pain comparing TEP to Lichtenstein repair: the TEPLICH RCT 8 years follow-up.Hernia : the journal of hernias and abdominal wall surgery · 2024
    Trial
  6. Trial
  7. Article
  8. Long-Term Outcomes Following Inguinal Hernia Repair With Mesh Performed by Medical Doctors and Surgeons in Ghana.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024
    Article
  9. Fixation techniques in inguinal hernia repair, what is really new?Hernia : the journal of hernias and abdominal wall surgery · 2020
    Article
  10. [Evidence-based Lichtenstein technique].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2017
    Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

M MatikainenDepartment of Surgery, Kuopio University Hospital, Kuopio, Finland. markku.matikainen@pkssk.fi.
J KössiDepartment of Surgery, Paijat-Hame Central Hospital, Lahti, Finland.
S SilvastiDepartment of Surgery, North Karelia Central Hospital, Joensuu, Finland.
T HulmiDepartment of Surgery, North Karelia Central Hospital, Joensuu, Finland.
H PaajanenDepartment of Surgery, Kuopio University Hospital, Kuopio, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLichtenstein hernioplasty has relatively low recurrence rate, but chronic inguinal pain may cause harm to the patient. The aim of our study was to compare long-term results of cyanoacrylate glue versus absorbable sutures for mesh fixation in Lichtenstein hernioplasty.

methodsLichtenstein hernioplasty (n = 302) was performed under local anesthesia in three hospitals. The patients were randomized to receive either 1 ml of butyl-2-cyanoacrylate tissue glue (Glubran

resultsWe reached 236 patients (78%) to present study. In the glue group (n = 115), there were five (4.3%) and in the suture group (n = 121) three (2.5%) recurrent hernias (p = 0.491). The prevalence of chronic pain (NRS ≥ 3) in the patients without re-operations was similar in two groups: 15/118 (13%) and 13/111 (12%), respectively (p = 0.843). There were no significant differences in the foreign body sensation (8/14, p = 0.267) or in the need of analgesics (2/2, p = 1.00) between the two study groups.

conclusionBoth cyanoacrylate glue and mesh fixation with absorbable sutures were equal in terms of chronic pain and rate of recurrences in Lichtenstein hernioplasty after 7-year follow-up. TRIAL REGISTRATION NUMBER: NCT00659542.

Indexed as

CyanoacrylatesSurgical MeshSuture TechniquesTissue AdhesivesAdultAgedChronic PainFemaleFollow-Up StudiesHernia, InguinalHerniorrhaphyHumansMaleMiddle AgedPolyglycolic AcidPostoperative PainCyanoacrylatesglubranPolyglycolic AcidTissue Adhesives

Identifiers

PMID27864616

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.