Evidence map›Paper›PMID 27864578›Full record

ArticleThe neuroradiology journal2017

Mesoscopic imaging of glioblastomas: Are diffusion, perfusion and spectroscopic measures influenced by the radiogenetic phenotype?

Theo Demerath, Carl Philipp Simon-Gabriel, Elias Kellner, Ralf Schwarzwald, Thomas Lange, Dieter Henrik Heiland, Peter Reinacher, Ori Staszewski, Hansjörg Mast, Valerij G Kiselev and 4 more

Open access · greenAbstract read
In one paragraph

Article in The neuroradiology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Radiogenomic Analysis of Oncological Data: A Technical Survey.International journal of molecular sciences · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Theo Demerath1 Department of Neuroradiology, Medical Centre-University of Freiburg, Germany.
Carl Philipp Simon-Gabriel1 Department of Neuroradiology, Medical Centre-University of Freiburg, Germany.
Elias Kellner3 Faculty of Medicine, University of Freiburg, Germany.
Ralf Schwarzwald1 Department of Neuroradiology, Medical Centre-University of Freiburg, Germany.
Thomas Lange3 Faculty of Medicine, University of Freiburg, Germany.
Dieter Henrik Heiland3 Faculty of Medicine, University of Freiburg, Germany.
Peter Reinacher3 Faculty of Medicine, University of Freiburg, Germany.
Ori Staszewski3 Faculty of Medicine, University of Freiburg, Germany.
Hansjörg Mast1 Department of Neuroradiology, Medical Centre-University of Freiburg, Germany.
Valerij G Kiselev3 Faculty of Medicine, University of Freiburg, Germany.
Karl Egger1 Department of Neuroradiology, Medical Centre-University of Freiburg, Germany.
Horst Urbach1 Department of Neuroradiology, Medical Centre-University of Freiburg, Germany.
Astrid Weyerbrock3 Faculty of Medicine, University of Freiburg, Germany.
Irina Mader1 Department of Neuroradiology, Medical Centre-University of Freiburg, Germany.
University of Freiburg · DEUniversity Medical Center Freiburg · DEUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to identify markers from perfusion, diffusion, and chemical shift imaging in glioblastomas (GBMs) and to correlate them with genetically determined and previously published patterns of structural magnetic resonance (MR) imaging. Twenty-six patients (mean age 60 years, 13 female) with GBM were investigated. Imaging consisted of native and contrast-enhanced 3D data, perfusion, diffusion, and spectroscopic imaging. In the presence of minor necrosis, cerebral blood volume (CBV) was higher (median ± SD, 2.23% ± 0.93) than in pronounced necrosis (1.02% ± 0.71), p

Indexed as

Diagnostic ImagingAdultAgedAged, 80 and overBrain NeoplasmsDiffusion Magnetic Resonance ImagingFemaleGlioblastomaHumansImaging, Three-DimensionalIsocitrate DehydrogenaseKi-67 AntigenMagnetic Resonance AngiographyMagnetic Resonance SpectroscopyMaleMiddle AgedIDH1 protein, humanIsocitrate DehydrogenaseKi-67 Antigendiffusion imagingglioblastomaperfusion imagingproton spectroscopyRadiogenomics

Identifiers

PMID27864578
PMCPMC5564334
OpenAlexW2554357424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.