Evidence map›Paper›PMID 27864507›Full record

ArticleJournal of radiation research2017

Multicentre dose audit for clinical trials of radiation therapy in Asia.

Hideyuki Mizuno, Shigekazu Fukuda, Akifumi Fukumura, Yuzuru-Kutsutani Nakamura, Cao Jianping, Chul-Koo Cho, Nana Supriana, To Anh Dung, Miriam Joy Calaguas, C R Beena Devi and 7 more

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In one paragraph

Article in Journal of radiation research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Hideyuki MizunoDepartment of Radiation Measurement and Dose Assessment,National Institute of Radiological Sciences (NIRS), National Institutes for Quantum and Radiological Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.
Shigekazu FukudaDepartment of Radiation Measurement and Dose Assessment,National Institute of Radiological Sciences (NIRS), National Institutes for Quantum and Radiological Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.
Akifumi FukumuraDepartment of Radiation Measurement and Dose Assessment,National Institute of Radiological Sciences (NIRS), National Institutes for Quantum and Radiological Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.
Yuzuru-Kutsutani NakamuraDepartment of Radiation Measurement and Dose Assessment,National Institute of Radiological Sciences (NIRS), National Institutes for Quantum and Radiological Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.
Cao JianpingSoochow University,China.
Chul-Koo ChoKorea Institute of Radiological & Medical Sciences (KIRAMS), Korea.
Nana SuprianaCipto Mangunkusumo Hospital, Indonesia.
To Anh DungNational Cancer Hospital, Vietnam.
Miriam Joy CalaguasSt Luke's Medical Center, Philippines.
C R Beena DeviSarawak General Hospital, Malaysia.
Yaowalak ChansilpaSiriraj Hospital, Mahidol University, Thailand.
Parvin Akhter BanuDelta Hospital Ltd, Bangladesh.
Masooma RiazInstitute of Nuclear Medicine and Oncology, Pakistan.
Surya EsentayevaKazakh Research Institute of Oncology and Radiology, Kazakhstan.
Shingo KatoSaitama Medical University International Medical Centre, Japan.
Kumiko KarasawaTokyo Women's Medical University Hospital, Japan.
Hirohiko TsujiiDepartment of Radiation Measurement and Dose Assessment,National Institute of Radiological Sciences (NIRS), National Institutes for Quantum and Radiological Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A dose audit of 16 facilities in 11 countries has been performed within the framework of the Forum for Nuclear Cooperation in Asia (FNCA) quality assurance program. The quality of radiation dosimetry varies because of the large variation in radiation therapy among the participating countries. One of the most important aspects of international multicentre clinical trials is uniformity of absolute dose between centres. The National Institute of Radiological Sciences (NIRS) in Japan has conducted a dose audit of participating countries since 2006 by using radiophotoluminescent glass dosimeters (RGDs). RGDs have been successfully applied to a domestic postal dose audit in Japan. The authors used the same audit system to perform a dose audit of the FNCA countries. The average and standard deviation of the relative deviation between the measured and intended dose among 46 beams was 0.4% and 1.5% (k = 1), respectively. This is an excellent level of uniformity for the multicountry data. However, of the 46 beams measured, a single beam exceeded the permitted tolerance level of ±5%. We investigated the cause for this and solved the problem. This event highlights the importance of external audits in radiation therapy.

Indexed as

Clinical AuditClinical Trials as TopicDose-Response Relationship, RadiationMulticenter Studies as TopicRadiometryAsiaHumansSurveys and Questionnairesdose auditdosimetryforum for nuclear cooperation in Asialinacradiophotoluminescent glass dosimeter

Identifiers

PMID27864507
PMCPMC5440882

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.