Evidence map›Paper›PMID 27864318›Full record

ArticleHeart (British Cardiac Society)2017

Coronary heart disease and risk factors as predictors of trajectories of psychological distress from midlife to old age.

Marianna Virtanen, Marko Elovainio, Kim Josefsson, G David Batty, Archana Singh-Manoux, Mika Kivimäki

Abstract read
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Article in Heart (British Cardiac Society), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. The Age-Dependent Association Between Vascular Risk Factors and Depressed Mood.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022
    Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Marianna VirtanenFinnish Institute of Occupational Health, Helsinki, Finland.
Marko ElovainioNational Institute for Health and Welfare, Helsinki, Finland.
Kim JosefssonNational Institute for Health and Welfare, Helsinki, Finland.
G David BattyDepartment of Epidemiology and Public Health, University College London, London, UK.
Archana Singh-ManouxDepartment of Epidemiology and Public Health, University College London, London, UK.
Mika KivimäkiFinnish Institute of Occupational Health, Helsinki, Finland.

Funding

Socio-economic status and heterogeneity in agingR01AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G, SINGH-MANOUX, ARCHANA · 1996 to 2013
$3.5M
Socioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1M
Health behaviors over the adult lifecourse and cognitive agingR01AG034454 · NIA · UNIVERSITY COLLEGE LONDON · PI KIVIMAKI, MIKA J, SINGH-MANOUX, ARCHANA · 2009 to 2013
$1.5M
British Heart Foundation RG/13/2/30098Medical Research Council K013351Medical Research Council MR/K013351/1NHLBI NIH HHS R01 HL036310NIA NIH HHS R01 AG013196NIA NIH HHS R01 AG034454
6 · The paper itself

Abstract

objectiveTo examine coronary heart disease (CHD) and its risk factors as predictors of long-term trajectories of psychological distress from midlife to old age.

methodsIn the Whitehall II cohort study, 6890 participants (4814 men, 2076 women; mean age 49.5 years) had up to seven repeat assessments of psychological distress over 21 years (mean follow-up 19 years). CHD and its risk factors (lifestyle-related risk factors, diabetes, hypertension and cholesterol) were assessed at baseline. Group-based trajectory modelling was used to identify clusters of individuals with a similar pattern of psychological distress over time.

resultsWe identified four trajectories of psychological distress over the follow-up: 'persistently low' (69% of the participants), 'persistently intermediate' (13%), 'intermediate to low' (12%) and 'persistently high' (7%). The corresponding proportions were 60%, 16%, 13% and 11% among participants with CHD; 63%, 15%, 12% and 10% among smokers and 63%, 16%, 12% and 10% among obese participants. In multivariable adjusted multinomial regression analyses comparing other trajectories to persistently low trajectory, prevalent CHD was associated with intermediate to low (OR 1.70, 95% CI 1.08 to 2.68) and persistently high (OR 1.92, 95% CI 1.16 to 3.19) trajectories. Smoking (OR 1.33, 95% CI 1.07 to 1.64; OR 1.55, 95% CI 1.19 to 2.04) and obesity (OR 1.33, 95% CI 1.04 to 1.70; OR 1.47, 95% CI 1.07 to 2.01) were associated with persistently intermediate and persistently high trajectories, respectively.

conclusionCHD, smoking and obesity may have a role in the development of long-lasting psychological distress from midlife to old age.

Indexed as

AdultAge FactorsAgingComorbidityCoronary DiseaseFemaleHumansLife StyleLondonLongitudinal StudiesMaleMiddle AgedMultivariate AnalysisNonlinear DynamicsObesityOdds Ratio

Identifiers

PMID27864318
PMCPMC5529979

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.