ReviewWiley interdisciplinary reviews. Systems biology and medicine2017
Modeling, signaling and cytoskeleton dynamics: integrated modeling-experimental frameworks in cell migration.
Review in Wiley interdisciplinary reviews. Systems biology and medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Rules of life at the interface of calcium signaling and mechanobiology.APL bioengineering · 2025Review
- Retinoic-Acid-Related Orphan Receptor Alpha Is Involved in the Regulation of the Cytoskeleton of Hair Follicle Stem Cells.Biomolecules · 2025Article
- Unravelling cell migration: defining movement from the cell surface.Cell adhesion & migration · 2022Review
- Density-Dependent Migration Characteristics of Cancer Cells Driven by Pseudopod Interaction.Frontiers in cell and developmental biology · 2022Article
- Computational models of migration modes improve our understanding of metastasis.APL bioengineering · 2020Review
- Bridging from single to collective cell migration: A review of models and links to experiments.PLoS computational biology · 2020Review
- Hyaluronic acid induces ROCK-dependent amoeboid migration in glioblastoma cells.Biomaterials science · 2020Article
- Integrated in silico and 3D in vitro model of macrophage migration in response to physical and chemical factors in the tumor microenvironment.Integrative biology : quantitative biosciences from nano to macro · 2020Article
- A 5-Gene Stemness Score for Rapid Determination of Risk in Multiple Myeloma.OncoTargets and therapy · 2020Article
- From energy to cellular forces in the Cellular Potts Model: An algorithmic approach.PLoS computational biology · 2019Article
- Are the Effects of Independent Biophysical Factors Linearly Additive? A 3D Tumor Migration Model.Biophysical journal · 2019Article
- Article
- Computational modeling of single-cell mechanics and cytoskeletal mechanobiology.Wiley interdisciplinary reviews. Systems biology and medicine · 2018Review
- Integrins in T Cell Physiology.International journal of molecular sciences · 2018Review
- Integration ofFrontiers in physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Cell migration is a complex and multistep process involved in homeostasis maintenance, morphogenesis, and disease development, such as cancer metastasis. Modeling cell migration and the relevant cytoskeleton dynamics have profound implications for studying fundamental development and disease diagnosis. This review focuses on some recent models of both cell migration and migration-related cytoskeleton dynamics, addressing issues such as the difference between amoeboid and mesenchymal migration modes, and between single-cell migration and collective cell migration. The review also highlights the computational integration among variable external cues, especially the biochemical and mechanical signaling that affects cell migration. Finally, we aim to identify the gaps in our current knowledge and potential strategies to develop integrated modeling-experimental frameworks for multiscale behavior integrating gene expression, cell signaling, mechanics, and multicellular dynamics. WIREs Syst Biol Med 2017, 9:e1365. doi: 10.1002/wsbm.1365 For further resources related to this article, please visit the WIREs website.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.