Evidence map›Paper›PMID 27862936›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2017

Branched Gold Nanoparticle Coating of Clostridium novyi-NT Spores for CT-Guided Intratumoral Injection.

Wooram Park, Soojeong Cho, Xiaoke Huang, Andrew C Larson, Dong-Hyun Kim

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Metabolic Gadolinium Labeling ofBiomaterials research · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Recent advances in bacteria-mediated cancer therapy.Frontiers in bioengineering and biotechnology · 2022
    Review
  15. Contrast-enhanced proton radiographic sensitivity limits for tumor detection.Journal of medical imaging (Bellingham, Wash.) · 2021
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wooram ParkDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Soojeong ChoDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Xiaoke HuangDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Andrew C LarsonDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Dong-Hyun KimDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Quantitative MRI-Guided Nanoembolization for Liver CancerR01CA159178 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LARSON, ANDREW CHRISTIAN, OMARY, REED A. · 2011 to 2015
$2.4M
MRI-Monitored Delivery of Sorafenib-Eluting Microspheres to Liver TumorsR01CA181658 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LARSON, ANDREW CHRISTIAN · 2015 to 2019
$2.1M
MRI of Iron-labeled Microsphere Biodistribution for Radioembolization DosimetryR01CA141047 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LARSON, ANDREW CHRISTIAN · 2010 to 2013
$1.2M
Magnetic Nanocomposites for Catheter-Directed Drug Delivery to Liver TumorsR21EB017986 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2014 to 2015
$425k
Magnetic Micelles for Catheter-Directed Sorafenib Delivery to Liver TumorsR21CA185274 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2015 to 2016
$367k
Targeted Transcatheter Magneto-Mechanical Therapy for Hepatocellular CarcinomaR21CA173491 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2013 to 2014
$364k
NCATS NIH HHS UL1 TR001422NCI NIH HHS P30 CA060553NCI NIH HHS R01 CA141047NCI NIH HHS R01 CA159178NCI NIH HHS R01 CA181658NCI NIH HHS R21 CA173491NCI NIH HHS R21 CA185274NIBIB NIH HHS R21 EB017986
6 · The paper itself

Abstract

Branched gold nanoparticle (BGNP)-coated Clostridium novyi-NT (C. novyi-NT) spores are developed for computed tomography (CT)-guided bacteriolytic tumor therapy. The BGNP-coated spores are successfully injected into a tumor site under CT image guidance. As a result, a strong antitumor effect is observed in a PC3 prostate tumor-bearing mouse model.

Indexed as

ClostridiumColloidsElectrochemistryGoldInjections, IntralesionalMetal NanoparticlesSpores, BacterialUltrasonicsColloidsGoldbacteriolytic tumor therapyClostridium novyi-NTcomputed tomography image-guided therapygold nanoparticles

Identifiers

PMID27862936
PMCPMC5288294

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.