Evidence map›Paper›PMID 27862883›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2017

The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology.

A Loupy, M Haas, K Solez, L Racusen, D Glotz, D Seron, B J Nankivell, R B Colvin, M Afrouzian, E Akalin and 27 more

2 registry-linked trialsAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 279 papers.

0numbers the graph read from it
0cells of the map it votes in
279citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03436134 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Treatment of Chronic Active Antibody Mediated Rejection After Kidney Transplantation by Double-Filtration PlasmaPheresis (DFPP) or Plasma Exchange (PE).

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2018 to 2021Enrolled16ConditionsKidney Transplantation, Antibody Mediated RejectionArmsSessions of conventional apheresis, Sessions of news apheresis with double filtration
NCT05306795 unknown statusnot on this map

Development, Application, and Validation of a Comprehensive Classification Automation System for Allograft Precision Diagnostics in Adult and Pediatric Kidney Transplant Biopsies

TypeobservationalSponsorParis Translational Research Center for Organ TransplantationRan2016 to 2022Enrolled4,000ConditionsKidney Transplant Rejection, Pathology
3 · Its place in the literature

Who cites it

279 citing papers in PubMed.

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219 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

A LoupyParis Translational Research Center for Organ Transplantation INSERM U970 & Necker Hospital University Paris Descartes, Paris, France.
M HaasDepartment of Pathology & Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.
K SolezDepartment of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada.
L RacusenDepartment of Laboratory Medicine and Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
D GlotzParis Translational Research Center for Organ Transplantation & Department of Nephrology and Transplantation, Hopital Saint Louis, Université Paris VII and INSERM U 1160, Paris, France.
D SeronNephrology Department, Hospital Vall d'Hebron, Autonomous University of Barcelona, Barcelona, Spain.
B J NankivellDepartment of Renal Medicine, Westmead Hospital, Sydney, Australia.
R B ColvinDepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
M AfrouzianDepartments of Pathology & Internal Medicine, University of Texas Medical Branch, Galveston, TX.
E AkalinMontefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.
N AlachkarDivision of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
S BagnascoDepartment of Laboratory Medicine and Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
J U BeckerInstitute of Pathology, University Hospital of Cologne, Cologne, Germany.
L CornellDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
C DrachenbergUniversity of Maryland School of Medicine, Baltimore, MD.
D DragunBerlin Institute of Health and Department of Nephrology and Critical Care Medicine, Charité Universitätsmedizin, Berlin, Germany.
H de KortDepartment of Nephrology, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0003-3601-532X
I W GibsonDepartment of Pathology, University of Manitoba, Winnipeg, Canada.
E S KrausDivision of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
C LefaucheurParis Translational Research Center for Organ Transplantation & Department of Nephrology and Transplantation, Hopital Saint Louis, Université Paris VII and INSERM U 1160, Paris, France.
C LegendreParis Translational Research Center for Organ Transplantation INSERM U970 & Necker Hospital University Paris Descartes, Paris, France.
H LiapisDepartment of Pathology & Immunology, Washington University, St. Louis, MO.
T MuthukumarDivision of Nephrology and Hypertension, Department of Medicine, New York Presbyterian Hospital-Weill Cornell Medicine, New York, NY.
V NickeleitDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC.
B OrandiDivision of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
W ParkDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
M RabantParis Translational Research Center for Organ Transplantation INSERM U970 & Necker Hospital University Paris Descartes, Paris, France.
P RandhawaDivision of Transplantation Pathology, The Thomas E Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.
E F ReedDepartment of Pathology and Laboratory Medicine, University of California, Los Angeles, CA.
C RoufosseDepartment of Cellular Pathology, Hammersmith Hospital, London, UK.
S V SeshanDepartment of Pathology, Weill Cornell Medicine, New York, NY.
B SisDepartment of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada.
H K SinghDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC.
C SchinstockDivision of Nephrology, Mayo Clinic, Rochester, MN.
A TamburComprehensive Transplant Center, Transplant Immunology Laboratory, Northwestern University, Chicago, IL.
A ZeeviUniversity of Pittsburgh Medical Center, Pittsburgh, PA.
M MengelDepartment of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada.

Funding

CIHR
6 · The paper itself

Abstract

The XIII Banff meeting, held in conjunction the Canadian Society of Transplantation in Vancouver, Canada, reviewed the clinical impact of updates of C4d-negative antibody-mediated rejection (ABMR) from the 2013 meeting, reports from active Banff Working Groups, the relationships of donor-specific antibody tests (anti-HLA and non-HLA) with transplant histopathology, and questions of molecular transplant diagnostics. The use of transcriptome gene sets, their resultant diagnostic classifiers, or common key genes to supplement the diagnosis and classification of rejection requires further consensus agreement and validation in biopsies. Newly introduced concepts include the i-IFTA score, comprising inflammation within areas of fibrosis and atrophy and acceptance of transplant arteriolopathy within the descriptions of chronic active T cell-mediated rejection (TCMR) or chronic ABMR. The pattern of mixed TCMR and ABMR was increasingly recognized. This report also includes improved definitions of TCMR and ABMR in pancreas transplants with specification of vascular lesions and prospects for defining a vascularized composite allograft rejection classification. The goal of the Banff process is ongoing integration of advances in histologic, serologic, and molecular diagnostic techniques to produce a consensus-based reporting system that offers precise composite scores, accurate routine diagnostics, and applicability to next-generation clinical trials.

Indexed as

ArteritisComplement C4bGraft RejectionHumansIsoantibodiesKidney TransplantationPeptide FragmentsResearch ReportComplement C4bcomplement C4dIsoantibodiesPeptide Fragmentsclinical research/practicekidney transplantation/nephrologyorgan transplantation in generalpathology/histopathologyrejectionrejection: antibody-mediated (ABMR)rejection: subclinicalrejection: T cell mediated (TCMR)translational research/science

Identifiers

PMID27862883
PMCPMC5363228

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.